Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | SLC5A1 | P13866 | 2/20 | 0.31 |
| ▸ | SLC5A2 | P31639 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18509002 | 0.90 | TRPA1 (0.38) | TRPA1CNR2OPRM1 | |
| SCHEMBL13861855 | 0.80 | BRD4 (0.31) | NOTUM | |
| SCHEMBL31267399 | 0.77 | SELL (0.37) | TRPA1NOTUM | |
| SCHEMBL18508826 | 0.77 | SELL (0.37) | TRPA1NOTUM | |
| SCHEMBL13131908 | 0.75 | CA12 (0.47) | NPC1RAB9A | |
| SCHEMBL7489213 | 0.74 | PARP1 (0.47) | NOTUM | |
| SCHEMBL19346099 | 0.74 | TRPA1 (0.39) | TRPA1SLC5A1SLC5A2RAB9A | |
| SCHEMBL13114495 | 0.74 | ALOX15 (0.38) | NOTUM | |
| SCHEMBL18601207 | 0.72 | PTGS2 (0.47) | CNR2NPC1RAB9A | |
| SCHEMBL19679266 | 0.72 | TRPA1 (0.45) | TRPA1CNR2OPRM1SLC5A1SLC5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2168952-B1 | MORPHOLINE DERIVATIVES AS RENIN INHIBITORS | MITSUBISHI TANABE PHARMA CORP (JP) | 2017-02-15 | — | — | EP | disclosed |