Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | MAOA | P21397 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | GLA | P06280 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30487670 | 0.80 | L3MBTL1 (0.42) | KDM4EALDH1A1MAOAHSD17B10GLA | |
| SCHEMBL30633823 | 0.73 | MAOA (0.53) | KDM4EALDH1A1MAOAHSD17B10GLA | |
| SCHEMBL5482188 | 0.73 | ALDH1A1 (0.52) | KDM4EALDH1A1MAOAHSD17B10GLA | |
| SCHEMBL18263654 | 0.71 | MCL1 (0.54) | KDM4ESMN1; SMN2MCL1HDAC6GABRP | |
| SCHEMBL1875230 | 0.71 | MAPT (0.45) | KDM4EALDH1A1MAOAHSD17B10GLA | |
| SCHEMBL2389722 | 0.69 | ERCC5 (0.52) | KDM4EALDH1A1HSD17B10GLAMAPT | |
| SCHEMBL1287815 | 0.68 | MCL1 (0.46) | KDM4EALDH1A1HSD17B10HPGDCYP3A4 | |
| SCHEMBL13102148 | 0.67 | MEN1 (0.60) | KDM4EALDH1A1HSD17B10GLAMAPT | |
| SCHEMBL25278009 | 0.67 | KDM4E (0.50) | KDM4ESMN1; SMN2HDAC6GABRPGABRD | |
| Xanthone SCHEMBL41161 | 0.66 | MAOA (1.00) | KDM4EALDH1A1MAOAHSD17B10GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117860753-A | CDC7 inhibitor compound XL413 for preparing medicine for preventing or treating liver injury and liver fibrosis and application thereof | 华中科技大学 | 2024-04-12 | — | — | CN | claimed |
| CN-117590707-B | Preparation method of pixel defining layer | DUK SAN NEOLUX CO.,LTD. (KR) | 2026-05-26 | — | — | CN | disclosed |
| US-20250290099-A1 | MATERIALS AND METHODS FOR TARGETED GENETIC MANIPULATIONS IN CELLS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2025-09-18 | — | — | US | disclosed |
| CN-120051168-A | Preparation method of pixel defining layer | 德山新勒克斯有限公司 | 2025-05-27 | — | — | CN | disclosed |
| CN-120051169-A | Preparation method of pixel defining layer | 德山新勒克斯有限公司 | 2025-05-27 | — | — | CN | disclosed |
| CN-119859265-A | Polybenzoxazole-based or polyimide-based precursor, copolymer thereof, and positive photosensitive composition containing same | 德山新勒克斯有限公司 | 2025-04-22 | — | — | CN | disclosed |
| CN-119859263-A | Polyimide-based precursor and composition containing same | 德山新勒克斯有限公司 | 2025-04-22 | — | — | CN | disclosed |
| CN-119836183-A | Preparation method of pixel defining layer | 德山新勒克斯有限公司 | 2025-04-15 | — | — | CN | disclosed |
| CN-119730675-A | Preparation method of pixel defining layer | 德山新勒克斯有限公司 | 2025-03-28 | — | — | CN | disclosed |
| CN-115023414-B | Compound for organic electronic element, organic electronic element using the same, and electronic device using the same | 德山新勒克斯有限公司 | 2025-03-28 | — | — | CN | disclosed |
| CN-115023414-A | Compound for organic electric element, organic electric element using the same, and electronic device thereof | 德山新勒克斯有限公司 | 2022-09-06 | — | — | CN | disclosed |
| US-10745410-B2 | Substituted [5,6]cyclic-4(3H)-pyrimidinones as anticancer agents | ZENJI RESEARCH LABORATORIES (CN) | 2020-08-18 | — | — | US | disclosed |
| US-20200055867-A1 | SUBSTITUTED [5,6]CYCLIC-4(3H)-PYRIMIDINONES AS ANTICANCER AGENTS | ZENJI RESEARCH LABORATORIES (CN) | 2020-02-20 | — | — | US | disclosed |
| WO-2018217439-A1 | SUBSTITUTED [5,6]CYCLIC-4(3H)-PYRIMIDINONES AS ANTICANCER AGENTS | ZHANG HAI JUN (US) | 2018-11-29 | — | — | WO | disclosed |
| EP-2097419-B1 | BENZOFUROPYRIMIDINONES AS PROTEIN KINASE INHIBITORS | EXELIXIS INC (US) | 2011-05-25 | — | — | EP | disclosed |
| CN-101965351-A | Benzofuran pyrimidinones | EXELIXIS INC | 2011-02-02 | — | — | CN | disclosed |
| US-20090247559-A1 | Benzofuropyrimidinones | EXELIXIS, INC. (US) | 2009-10-01 | — | — | US | disclosed |
| US-20090247559-A1 | Benzofuropyrimidinones | EXELIXIS, INC. (US) | 2009-10-01 | — | — | US | disclosed |
| EP-2097419-A1 | BENZOFUROPYRIMIDINONES AS PROTEIN KINASE INHIBITORS | Exelixis, Inc. (US) | 2009-09-09 | — | — | EP | disclosed |
| WO-2009086264-A1 | BENZOFUROPYRIMIDINONES AS PROTEIN KINASE INHIBITORS | EXELIXIS, INC. (US) | 2009-07-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200055867-A1 | SUBSTITUTED [5,6]CYCLIC-4(3H)-PYRIMIDINONES AS ANTICANCER AGENTS | CDC7, CDK7, CDK17 | KDM4E 1123/4885ALDH1A1 3194/4885MAOA 4606/4885 |
| US-20090247559-A1 | Benzofuropyrimidinones | F12, BRI3BP, BRD1 | KDM4E 1855/4885ALDH1A1 315/4885MAOA 1456/4885 |
| US-10745410-B2 | Substituted [5,6]cyclic-4(3H)-pyrimidinones as anticancer agents | CDC7, CDK7, CDK17 | KDM4E 1123/4885ALDH1A1 3194/4885MAOA 4606/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.