Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.57 |
| ▸ | TSHR | P16473 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | MAPK10 | P53779 | 4/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 8/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | AHR | P35869 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1852416 | 0.89 | HPGD (0.58) | HPGDALDH1A1KMT2AHSD17B10TSHR | |
| SCHEMBL4125534 | 0.79 | HPGD (0.55) | HPGDALDH1A1KMT2AHSD17B10TSHR | |
| SCHEMBL1852418 | 0.77 | HPGD (0.53) | HPGDALDH1A1KMT2AHSD17B10TSHR | |
| SCHEMBL13699719 | 0.77 | MAPT (0.60) | HPGDALDH1A1KMT2AHSD17B10TSHR | |
| SCHEMBL1853596 | 0.77 | HPGD (0.52) | HPGDALDH1A1KMT2AHSD17B10TSHR | |
| SCHEMBL1850908 | 0.74 | ALDH1A1 (0.49) | HPGDALDH1A1KMT2AHSD17B10TSHR | |
| SCHEMBL1852128 | 0.74 | HPGD (0.55) | HPGDALDH1A1KMT2AHSD17B10TSHR | |
| SCHEMBL1851522 | 0.74 | MAPT (0.57) | HPGDALDH1A1KMT2AHSD17B10TSHR | |
| SCHEMBL4552452 | 0.73 | TSHR (0.52) | HPGDALDH1A1KMT2AHSD17B10TSHR | |
| SCHEMBL1854355 | 0.72 | KMT2A (0.43) | HPGDALDH1A1KMT2AHSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2097419-B1 | BENZOFUROPYRIMIDINONES AS PROTEIN KINASE INHIBITORS | EXELIXIS INC (US) | 2011-05-25 | — | — | EP | disclosed |