Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 6/20 | 0.43 |
| ▸ | CDK2 | P24941 | 6/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | CDK4 | P11802 | 1/20 | 0.38 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.38 |
| ▸ | CCND1 | P24385 | 1/20 | 0.38 |
| ▸ | CDK7 | P50613 | 1/20 | 0.38 |
| ▸ | CCNH | P51946 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.35 |
| ▸ | MTOR | P42345 | 3/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13168778 | 0.84 | MTOR (0.45) | CCNA2CDK2CHEK1MAPTGAA | |
| SCHEMBL13131376 | 0.75 | CCNA2 (0.42) | CCNA2CDK2MAPTGAACDK1 | |
| SCHEMBL30135101 | 0.71 | HTR6 (0.43) | CDK2MAPT | |
| SCHEMBL18509150 | 0.69 | ELANE (0.40) | — | |
| SCHEMBL18509010 | 0.67 | CCNA2 (0.47) | CCNA2CDK2CHEK1MAPTGAA | |
| SCHEMBL14462808 | 0.66 | CCNA2 (0.46) | CCNA2CDK2CHEK1MAPTGAA | |
| SCHEMBL14927060 | 0.63 | CCNC (0.51) | — | |
| Bromide SCHEMBL29018736 | 0.62 | CCNC (0.50) | — | |
| SCHEMBL8596327 | 0.62 | DHFR (0.49) | CHEK1MAPTCDK7PIK3CAGSK3B | |
| SCHEMBL25694338 | 0.62 | USP7 (0.40) | CHEK1MAPTCDK7PIK3CAGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2168952-B1 | MORPHOLINE DERIVATIVES AS RENIN INHIBITORS | MITSUBISHI TANABE PHARMA CORP (JP) | 2017-02-15 | — | — | EP | disclosed |