Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD2 | Q9NRG4 | 4/20 | 0.49 |
| ▸ | IKBKB | O14920 | 1/20 | 0.47 |
| ▸ | ERN1 | O75460 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | ATR | Q13535 | 2/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1850827 | 0.79 | SMYD2 (0.54) | SMYD2ERN1GPR52DRD4CYP2C9 | |
| SCHEMBL1851120 | 0.76 | GPR52 (0.53) | SMYD2IKBKBERN1KMT2AGPR52 | |
| SCHEMBL3211200 | 0.75 | SMYD2 (0.57) | SMYD2ERN1GPR52DRD4CYP2C9 | |
| SCHEMBL774938 | 0.71 | ERN1 (0.70) | SMYD2IKBKBERN1MEN1KMT2A | |
| SCHEMBL12203378 | 0.68 | MEN1 (0.76) | SMYD2ERN1MEN1KMT2AEPHX2 | |
| SCHEMBL1381550 | 0.66 | ALDH1A1 (0.70) | MEN1KMT2AAPPCYP2C9 | |
| SCHEMBL13060642 | 0.66 | ERN1 (0.62) | SMYD2ERN1MEN1KMT2AAPP | |
| SCHEMBL30765155 | 0.65 | SMN1; SMN2 (0.52) | SMYD2IKBKBERN1MEN1KMT2A | |
| SCHEMBL27260524 | 0.65 | SMN1; SMN2 (0.52) | SMYD2IKBKBERN1MEN1KMT2A | |
| SCHEMBL4502913 | 0.65 | CYP1A2 (0.73) | MEN1KMT2AAPPCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2323978-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2011-05-25 | — | — | EP | disclosed |
| WO-2010018874-A1 | AMIDE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-02-18 | — | — | WO | disclosed |