Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.41 |
| ▸ | P2RY12 | Q9H244 | 9/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18521449 | 0.93 | ADORA1 (0.43) | ADORA1 | |
| SCHEMBL24102381 | 0.85 | P2RY12 (0.40) | PRMT6P2RY12ADORA1 | |
| SCHEMBL4727394 | 0.83 | ADORA1 (0.46) | ADORA1 | |
| SCHEMBL4727404 | 0.83 | ADORA1 (0.46) | ADORA1 | |
| SCHEMBL25505318 | 0.83 | PRMT6 (0.39) | PRMT6P2RY12ADORA1 | |
| SCHEMBL21376284 | 0.81 | P2RY12 (0.40) | PRMT6P2RY12ADORA1 | |
| SCHEMBL25969465 | 0.80 | ADORA3 (0.52) | P2RY12 | |
| SCHEMBL25505312 | 0.80 | ADORA3 (0.52) | P2RY12 | |
| SCHEMBL25504687 | 0.80 | ADORA3 (0.52) | P2RY12 | |
| SCHEMBL14064199 | 0.80 | ADORA3 (0.52) | P2RY12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170044206-A1 | CYCLIC DI-NUCLEOTIDE COMPOUNDS AS STING AGONISTS | MERCK SHARP & DOHME CORP. (US) | 2017-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170044206-A1 | CYCLIC DI-NUCLEOTIDE COMPOUNDS AS STING AGONISTS | STING1, CGAS, IFNAR1 | PRMT6 3865/4885P2RY12 401/4885ADORA1 32/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.