Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.59 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.58 |
| ▸ | DPP4 | P27487 | 1/20 | 0.57 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.57 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.57 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.57 |
| ▸ | GAPDH | P04406 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.57 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.57 |
| ▸ | STAT6 | P42226 | 1/20 | 0.57 |
| ▸ | PI4KA | P42356 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.57 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.57 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.57 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.57 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16940285 | 0.91 | MEN1 (0.56) | MEN1KMT2AADORA3ADORA1DPP4 | |
| SCHEMBL19399434 | 0.91 | MEN1 (0.56) | MEN1KMT2AADORA3ADORA1DPP4 | |
| SCHEMBL26937463 | 0.91 | MEN1 (0.55) | MEN1KMT2AADORA3ADORA1DPP4 | |
| SCHEMBL20995821 | 0.89 | MEN1 (0.66) | MEN1KMT2AADORA3ADORA1DPP4 | |
| SCHEMBL658713 | 0.89 | MEN1 (0.66) | MEN1KMT2AADORA3ADORA1DPP4 | |
| SCHEMBL658714 | 0.89 | MEN1 (0.66) | MEN1KMT2AADORA3ADORA1DPP4 | |
| SCHEMBL29406864 | 0.89 | MEN1 (0.66) | MEN1KMT2AADORA3ADORA1DPP4 | |
| SCHEMBL23050294 | 0.88 | ADORA3 (0.75) | MEN1KMT2AADORA3ADORA1DPP4 | |
| SCHEMBL6635214 | 0.88 | MEN1 (0.65) | MEN1KMT2AADORA3ADORA1DPP4 | |
| SCHEMBL25936 | 0.88 | ADORA3 (0.75) | MEN1KMT2AADORA3ADORA1DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11339441-B2 | Profiling chemically modified DNA/RNA units for disease and cancer diagnosis | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2022-05-24 | — | — | US | disclosed |
| US-20170044619-A1 | PROFILING CHEMICALLY MODIFIED DNA/RNA UNITS FOR DISEASE AND CANCER DIAGNOSIS | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK | 2017-02-16 | — | — | US | disclosed |