Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28214326 | 0.75 | TDP1 (0.33) | — | |
| SCHEMBL8085073 | 0.75 | THRB (0.36) | — | |
| SCHEMBL22973238 | 0.73 | TSHR (0.39) | HTT | |
| SCHEMBL17350177 | 0.72 | TSHR (0.37) | — | |
| SCHEMBL472262 | 0.71 | TSHR (0.48) | — | |
| SCHEMBL238944 | 0.69 | TSHR (0.43) | — | |
| SCHEMBL18125076 | 0.69 | — | — | |
| SCHEMBL237000 | 0.68 | — | — | |
| SCHEMBL36595 | 0.67 | TSHR (0.48) | HTT | |
| SCHEMBL28031899 | 0.67 | TSHR (0.48) | HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017024408-A1 | ARYL-SUBSTITUTED DIHYDROQUINOLINONES, THEIR PREPARATION AND THEIR USE AS PHARMACEUTICALS | NEOMED INSTITUTE (CA) | 2017-02-16 | — | — | WO | disclosed |