Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | GUSB | P08236 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 2/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | MMP9 | P14780 | 2/20 | 0.36 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.35 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.35 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1851407 | 1.00 | MEN1 (0.38) | MEN1KMT2ACYP3A4MAPTTDP1 | |
| SCHEMBL1852736 | 0.86 | PTGS1 (0.43) | MEN1KMT2AMAPTSMN1; SMN2MMP1 | |
| SCHEMBL1852734 | 0.86 | PTGS1 (0.43) | MEN1KMT2AMAPTSMN1; SMN2MMP1 | |
| SCHEMBL3303703 | 0.83 | KMT2A (0.47) | MEN1KMT2ACYP3A4MAPTKDM4E | |
| SCHEMBL3303698 | 0.83 | KMT2A (0.47) | MEN1KMT2ACYP3A4MAPTKDM4E | |
| SCHEMBL13394645 | 0.82 | L3MBTL1 (0.45) | CYP3A4KDM4EALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL13394314 | 0.80 | SMN1; SMN2 (0.45) | MEN1KMT2AMAPTTDP1KDM4E | |
| SCHEMBL29186737 | 0.72 | GAA (0.44) | MEN1KMT2ACYP3A4MAPTKDM4E | |
| SCHEMBL13394308 | 0.69 | L3MBTL1 (0.68) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL14864458 | 0.69 | HTR6 (0.50) | MAPTALDH1A1THRBSMN1; SMN2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2323697-A2 | IMAGING AGENTS USEFUL FOR IDENTIFYING AD PATHOLOGY | Siemens Medical Solutions USA, Inc. (US) | 2011-05-25 | — | — | EP | disclosed |
| WO-2010011964-A2 | IMAGING AGENTS USEFUL FOR IDENTIFYING AD PATHOLOGY | SIEMENS MEDICAL SOLUTIONS USA, INC. (US) | 2010-01-28 | — | — | WO | disclosed |