Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GUCY1B2 | O75343 | 6/20 | 0.37 |
| ▸ | GUCY1A2 | P33402 | 6/20 | 0.37 |
| ▸ | GUCY1A1 | Q02108 | 6/20 | 0.37 |
| ▸ | GUCY1B1 | Q02153 | 6/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.35 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.35 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18749012 | 0.94 | RAB9A (0.40) | RAB9ANPC1ALDH1A1POLBGUCY1B2 | |
| SCHEMBL18514810 | 0.93 | RAB9A (0.39) | RAB9ANPC1ALDH1A1POLBGUCY1B2 | |
| SCHEMBL18513878 | 0.93 | RAB9A (0.39) | RAB9ANPC1ALDH1A1POLBGUCY1B2 | |
| SCHEMBL18514814 | 0.91 | SLC22A12 (0.41) | RAB9ANPC1ALDH1A1KDM4ESLC22A12 | |
| SCHEMBL18514787 | 0.90 | ALDH1A1 (0.43) | RAB9ANPC1ALDH1A1POLBKDM4E | |
| SCHEMBL18514972 | 0.90 | LMNA (0.38) | RAB9ANPC1ALDH1A1POLBKMT2A | |
| SCHEMBL18514819 | 0.90 | HPGD (0.38) | RAB9ANPC1ALDH1A1KMT2AKDM4E | |
| SCHEMBL18514818 | 0.89 | SLC22A12 (0.36) | RAB9ANPC1ALDH1A1KDM4ENPSR1 | |
| SCHEMBL18515141 | 0.89 | ALDH1A1 (0.43) | RAB9ANPC1ALDH1A1POLBGUCY1B2 | |
| SCHEMBL18515409 | 0.89 | ALDH1A1 (0.37) | RAB9ANPC1ALDH1A1POLBGUCY1B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9788547-B2 | Aromatic compound and uses thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-10-17 | — | — | US | disclosed |
| US-20170105413-A1 | AROMATIC COMPOUND AND USES THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-04-20 | — | — | US | disclosed |
| US-20170105416-A1 | AROMATIC COMPOUND AND USES THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-04-20 | — | — | US | disclosed |
| EP-3130584-A1 | AROMATIC COMPOUND AND USES THEREOF | Sumitomo Chemical Company Limited (JP) | 2017-02-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170105413-A1 | AROMATIC COMPOUND AND USES THEREOF | TYR, H1-3, H1-0 | RAB9A 143/4885NPC1 1784/4885ALDH1A1 1238/4885 |
| US-20170105416-A1 | AROMATIC COMPOUND AND USES THEREOF | TYR, H1-3, H1-10 | RAB9A 338/4885NPC1 2473/4885ALDH1A1 1416/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.