SCHEMBL671133

SCHEMBL671133

Clc1ccccc1-c1ccccc1Cl

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 2/20 0.67
LMNA P02545 2/20 0.64
TSHR P16473 2/20 0.64
DPP4 P27487 1/20 0.59
NPC1 O15118 2/20 0.55
RAB9A P51151 2/20 0.55
SMN1; SMN2 Q16637 2/20 0.55
HPGD P15428 2/20 0.55
TP53 P04637 1/20 0.55
PTPRC P08575 1/20 0.52
ALDH1A1 P00352 4/20 0.50
POLB P06746 1/20 0.50
KMT2A Q03164 1/20 0.50
PLA2G7 Q13093 1/20 0.50
HSD11B1 P28845 1/20 0.50
IDO1 P14902 2/20 0.48
NOTUM Q6P988 1/20 0.46
LDHA P00338 1/20 0.46
DNMT1 P26358 1/20 0.45
DNMT3L Q9UJW3 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29883244 1.00 CYP2A6 (0.67) CYP2A6LMNATSHRDPP4NPC1
SCHEMBL29802156 1.00 CYP2A6 (0.67) CYP2A6LMNATSHRDPP4NPC1
Ammonia Solution, Strong SCHEMBL735046 0.96 CYP2A6 (0.63) CYP2A6LMNATSHRDPP4NPC1
Hydrogen Sulfide SCHEMBL8574751 0.96 CYP2A6 (0.63) CYP2A6LMNATSHRDPP4NPC1
Hydrogen Sulfide SCHEMBL9195473 0.96 CYP2A6 (0.63) CYP2A6LMNATSHRDPP4NPC1
Ethyne SCHEMBL9861738 0.93 CYP2A6 (0.60) CYP2A6LMNATSHRDPP4NPC1
SCHEMBL10794320 0.87 CYP2A6 (0.55) CYP2A6LMNATSHRDPP4NPC1
SCHEMBL381601 0.85 CYP2A6 (0.52) CYP2A6LMNATSHRDPP4NPC1
Bicarbonate SCHEMBL4865957 0.85 CYP2A6 (0.59) CYP2A6LMNATSHRDPP4NPC1
Bicarbonate SCHEMBL11009844 0.85 CYP2A6 (0.59) CYP2A6LMNATSHRDPP4NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1902 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119361834-A Electrolyte and battery and electricity utilization device containing same 浙江大学 2025-01-24 CN claimed
EP-3265141-B1 COATING SCAFFOLDS TRS HOLDINGS LLC (US) 2024-11-13 EP claimed
CN-118234782-A Polyether copolymers based on glycol sugar alcohols 巴斯夫欧洲公司 2024-06-21 CN claimed
US-11981616-B2 Method for preparing 3,3′-diaminobenzidine Hubei Huida High-Tech Co., Ltd (CN) 2024-05-14 US claimed
US-20240109835-A1 METHOD FOR PREPARING 3,3'-DIAMINOBENZIDINE HUBEI HUIDA HIGH-TECH CO., LTD. (CN) 2024-04-04 US claimed
EP-4022623-B1 METHOD AND KIT TO PREDICT CELL DEATH IN RESPONSE TO BIOTIC AND/OR ABIOTIC STIMULI STAZIONE ZOOLOGICA ANTON DOHRN (IT) 2023-11-01 EP claimed
CN-116855058-A Low-temperature-resistant PC/ABS alloy and preparation method thereof 上海祺申塑业股份有限公司 2023-10-10 CN claimed
WO-2023146479-A1 A METHOD FOR PURIFICATION OF ORGANIC WATER-SOLUBLE POLYMERS FROM HYDROPHOBIC CONTAMINANTS USTAV EXPERIMENTALNEJ FYZIKY SLOVENSKEJ AKADEMIE VIED, VEREJNA VYSKUMNA INSTITUCIA (SK) 2023-08-03 WO claimed
EP-4219603-A1 A METHOD FOR PURIFICATION OF ORGANIC WATER-SOLUBLE POLYMERS FROM HYDROPHOBIC CONTAMINANTS Ustav experimentálnej fyziky SAV, v.v.i. (SK) 2023-08-02 EP claimed
CN-115108918-B Preparation method of 3,3', 4' -tetraminobiphenyl 湖北汇达科技发展有限公司 2023-06-02 CN claimed
US-5093468-A Heat resistant, moldings, fibers, films BAYER AKTIENGESELLSCHAFT (DE) 1992-03-03 US claimed
US-4873372-A Isolation of 4,4'-dichlorodiphenyl sulfone BASF AKTIENGESELLSCHAFT (DE) 1989-10-10 US claimed
US-4868275-A POLYTHIOETHERS TOSOH CORPORATION (JP) 1989-09-19 US claimed
US-4845190-A Process for preparing polyarylene sulfides with recovery of carboxylic acid TOSOH CORPORATION (JP) 1989-07-04 US claimed
EP-0304303-A2 Preparation of poly (arylene sulfide) Tosoh Corporation (JP) 1989-02-22 EP claimed
US-4789722-A SALT FORMATION, THEN REACTING WITH EXCESS OF DIHALOBENZENOID AND HYDROXY AROMATIC AMINE HERCULES INCORPORATED (US) 1988-12-06 US claimed
EP-0275687-A2 Process for preparing polyarylene sulfides Tosoh Corporation (JP) 1988-07-27 EP claimed
EP-0272903-A2 Process for producing a polyarylene sulfide Tosoh Corporation (JP) 1988-06-29 EP claimed
EP-0233966-A1 Polyarylene polyether made using mixed base system HERCULES INCORPORATED (US) 1987-09-02 EP claimed
US-4236973-A BY PASSING A CURRENT OF VAPOR THROUGH A MOVING STREAM TO VAPORIZE ANY ORGANICS THE DOW CHEMICAL COMPANY (US) 1980-12-02 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11981616-B2 Method for preparing 3,3′-diaminobenzidine CA3, DDT, DNPEP CYP2A6 648/4885LMNA 2693/4885TSHR 2858/4885
US-20240109835-A1 METHOD FOR PREPARING 3,3'-DIAMINOBENZIDINE CA3, DDT, DNPEP CYP2A6 434/4885LMNA 2494/4885TSHR 2747/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.