Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 14/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MC4R | P32245 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18516616 | 0.81 | SIGMAR1 (0.62) | SIGMAR1ALDH1A1 | |
| SCHEMBL10288974 | 0.81 | SIGMAR1 (0.62) | SIGMAR1ALDH1A1SMN1; SMN2MC4R | |
| SCHEMBL10223554 | 0.78 | SIGMAR1 (0.58) | SIGMAR1MC4R | |
| SCHEMBL18516703 | 0.78 | SIGMAR1 (0.58) | SIGMAR1MC4R | |
| SCHEMBL13675505 | 0.73 | SIGMAR1 (0.71) | SIGMAR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL18516696 | 0.73 | SIGMAR1 (0.60) | SIGMAR1ALDH1A1 | |
| SCHEMBL10288526 | 0.73 | SIGMAR1 (0.60) | SIGMAR1 | |
| SCHEMBL306766 | 0.72 | SIGMAR1 (0.54) | SIGMAR1 | |
| SCHEMBL307668 | 0.72 | SIGMAR1 (0.61) | SIGMAR1ALDH1A1 | |
| SCHEMBL13306955 | 0.71 | SIGMAR1 (0.73) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1957498-B1 | INHIBITORS OF VEGF RECEPTOR AND HGF RECEPTOR SIGNALING | METHYLGENE INC (CA) | 2017-02-15 | — | — | EP | disclosed |