Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEAD4 | Q15561 | 2/20 | 0.44 |
| ▸ | TEAD3 | Q99594 | 2/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | KDM1A | O60341 | 2/20 | 0.41 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.41 |
| ▸ | F12 | P00748 | 2/20 | 0.40 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.40 |
| ▸ | KLK7 | P49862 | 3/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | CTSG | P08311 | 2/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | TSLP | Q969D9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29875816 | 1.00 | TEAD4 (0.44) | TEAD4TEAD3OPRD1OPRK1OPRM1 | |
| SCHEMBL16021588 | 1.00 | TEAD4 (0.44) | TEAD4TEAD3OPRD1OPRK1OPRM1 | |
| SCHEMBL29875639 | 0.77 | KDM1A (0.43) | TEAD4TEAD3OPRD1OPRK1OPRM1 | |
| SCHEMBL13029942 | 0.73 | TEAD4 (0.40) | TEAD4TEAD3KDM1ARCOR1F12 | |
| SCHEMBL16023827 | 0.73 | KEAP1 (0.42) | OPRD1OPRK1OPRM1KDM1ARCOR1 | |
| SCHEMBL21973546 | 0.73 | KEAP1 (0.42) | OPRD1OPRK1OPRM1KDM1ARCOR1 | |
| SCHEMBL13029979 | 0.72 | TEAD4 (0.39) | TEAD4TEAD3KDM1ARCOR1F12 | |
| SCHEMBL20283327 | 0.71 | KLK7 (0.49) | OPRD1OPRK1OPRM1KLK7KEAP1 | |
| SCHEMBL29850820 | 0.66 | ACE (0.57) | — | |
| SCHEMBL22677563 | 0.65 | KDM1A (0.61) | KDM1ARCOR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200140489-A1 | Peptide-Based Quorum Sensing Inhibitors for the Attenuation of Virulence in Staphylococcus Aureus | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2020-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200140489-A1 | Peptide-Based Quorum Sensing Inhibitors for the Attenuation of Virulence in Staphylococcus Aureus | QRFPR, SCTR, SRRT | TEAD4 1771/4885TEAD3 2146/4885OPRD1 2897/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.