Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.39 |
| ▸ | MAPT | P10636 | 8/20 | 0.39 |
| ▸ | LMNA | P02545 | 7/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 4/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12665037 | 0.89 | ALDH1A1 (0.41) | ALDH1A1MAPTLMNAPOLBMAPK1 | |
| SCHEMBL14616552 | 0.87 | MAPT (0.39) | ALDH1A1MAPTLMNAPOLBMAPK1 | |
| SCHEMBL15290542 | 0.86 | MAPT (0.39) | ALDH1A1MAPTLMNAPOLBMAPK1 | |
| SCHEMBL14642912 | 0.86 | MAPT (0.39) | ALDH1A1MAPTLMNAPOLBMAPK1 | |
| SCHEMBL23187335 | 0.85 | MAPT (0.37) | ALDH1A1MAPTLMNAPOLBMAPK1 | |
| SCHEMBL23974128 | 0.85 | MAPT (0.46) | ALDH1A1MAPTLMNAPOLBMAPK1 | |
| SCHEMBL14616553 | 0.84 | MAPT (0.44) | ALDH1A1MAPTLMNAPOLBMAPK1 | |
| SCHEMBL26551381 | 0.84 | MAPT (0.37) | ALDH1A1MAPTLMNAPOLBMAPK1 | |
| SCHEMBL17231868 | 0.81 | MAPT (0.42) | ALDH1A1MAPTLMNAPOLBMAPK1 | |
| SCHEMBL12679101 | 0.81 | MAPT (0.42) | ALDH1A1MAPTLMNAPOLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023088236-A1 | BICYCLIC PEPTIDE LIGAND OF MT1-MMP AND CONJUGATE THEREOF | 海思科医药集团股份有限公司 | 2023-05-25 | — | — | WO | disclosed |
| WO-2023066314-A1 | BICYCLIC PEPTIDE LIGAND FOR NECTIN-4 AND USE THEREOF | 海思科医药集团股份有限公司 | 2023-04-27 | — | — | WO | disclosed |
| WO-2023061482-A1 | EPHA2 BICYCLIC PEPTIDE LIGAND AND CONJUGATE THEREOF | 海思科医药集团股份有限公司 | 2023-04-20 | — | — | WO | disclosed |
| US-11571480-B2 | Multi-ligand drug conjugates and uses thereof | Coherent Biopharma I, Limited (HK) | 2023-02-07 | — | — | US | disclosed |
| US-20220175761-A1 | BI-LIGAND DRUG CONJUGATE AND USE THEREOF | COHERENT BIOPHARMA SUZHOU LTD (CN) | 2022-06-09 | — | — | US | disclosed |
| EP-3903825-A1 | BI-LIGAND DRUG CONJUGATE AND USE THEREOF | Coherent Biopharma (Suzhou), Limited (CN) | 2021-11-03 | — | — | EP | disclosed |
| WO-2020156513-A1 | BI-LIGAND DRUG CONJUGATE AND USE THEREOF | 同宜医药（苏州）有限公司 | 2020-08-06 | — | — | WO | disclosed |
| US-20180200377-A1 | MULTI-LIGAND DRUG CONJUGATES AND USES THEREOF | Coherent Biopharma I, Limited (HK) | 2018-07-19 | — | — | US | disclosed |
| WO-2017025057-A1 | MULTI-LIGAND DRUG CONJUGATES AND USES THEREOF | COHERENT BIOPHARMA (KY) | 2017-02-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220175761-A1 | BI-LIGAND DRUG CONJUGATE AND USE THEREOF | SLC10A1, CD47, SELPLG | ALDH1A1 1722/4885MAPT 1034/4885LMNA 4163/4885 |
| US-11571480-B2 | Multi-ligand drug conjugates and uses thereof | CD44, CD47, SELPLG | ALDH1A1 1759/4885MAPT 2450/4885LMNA 3580/4885 |
| US-20180200377-A1 | MULTI-LIGAND DRUG CONJUGATES AND USES THEREOF | CD44, CD47, SELPLG | ALDH1A1 1759/4885MAPT 2450/4885LMNA 3580/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.