Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18519259 | 0.85 | ALDH1A1 (0.39) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL23187335 | 0.82 | MAPT (0.37) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL12665038 | 0.79 | ALDH1A1 (0.47) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL12665045 | 0.78 | MAPT (0.46) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL16018268 | 0.78 | LMNA (0.45) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL12673743 | 0.77 | MAPT (0.46) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL16016651 | 0.76 | LMNA (0.45) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL19733500 | 0.75 | MAPT (0.47) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL14616551 | 0.75 | LMNA (0.47) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL15290549 | 0.74 | LMNA (0.46) | MAPTALDH1A1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023066314-A1 | BICYCLIC PEPTIDE LIGAND FOR NECTIN-4 AND USE THEREOF | 海思科医药集团股份有限公司 | 2023-04-27 | — | — | WO | disclosed |
| EP-3903825-A1 | BI-LIGAND DRUG CONJUGATE AND USE THEREOF | Coherent Biopharma (Suzhou), Limited (CN) | 2021-11-03 | — | — | EP | disclosed |