Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 1/20 | 0.39 |
| ▸ | ADA | P00813 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20058638 | 0.85 | ADK (0.39) | ADKADA | |
| SCHEMBL14224892 | 0.75 | ADK (0.36) | ADKADA | |
| SCHEMBL22079614 | 0.73 | — | — | |
| SCHEMBL13924251 | 0.73 | IRAK4 (0.39) | ADK | |
| SCHEMBL4867832 | 0.72 | ADK (0.68) | ADK | |
| SCHEMBL21376205 | 0.72 | ADK (0.49) | ADK | |
| SCHEMBL14028811 | 0.72 | ADK (0.68) | ADK | |
| SCHEMBL20419034 | 0.72 | ADK (0.39) | ADK | |
| SCHEMBL13479945 | 0.70 | ADK (0.42) | ADK | |
| SCHEMBL20325350 | 0.68 | NT5E (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017027646-A1 | CYCLIC DI-NUCLEOTIDE COMPOUNDS AS STING AGONISTS | MERCK SHARP & DOHME CORP. (US) | 2017-02-16 | — | — | WO | disclosed |