Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | ADA | P00813 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18519939 | 0.85 | ADK (0.39) | ADKADA | |
| SCHEMBL14224892 | 0.75 | ADK (0.36) | ADKADORA3ADA | |
| SCHEMBL20419034 | 0.74 | ADK (0.39) | ADK | |
| SCHEMBL21376205 | 0.72 | ADK (0.49) | ADKADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL4867832 | 0.72 | ADK (0.68) | ADKADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL13479945 | 0.70 | ADK (0.42) | ADKADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL13924251 | 0.68 | IRAK4 (0.39) | ADKADORA2B | |
| SCHEMBL14544505 | 0.67 | ATG7 (0.47) | ADKADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL13408342 | 0.66 | PNP (0.49) | — | |
| SCHEMBL14628001 | 0.66 | ADK (0.51) | ADKADORA3ADORA2AADORA2BADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2906579-B1 | 2'-CHLORO NUCLEOSIDE ANALOGS FOR HCV INFECTION | IDENIX PHARMACEUTICALS LLC (US) | 2018-04-18 | — | — | EP | disclosed |