Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 3/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PI4KA | P42356 | 2/20 | 0.35 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.35 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.35 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.35 |
| ▸ | DOT1L | Q8TEK3 | 2/20 | 0.34 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.34 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.34 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | ROS1 | P08922 | 1/20 | 0.34 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.34 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.34 |
| ▸ | CLK2 | P49760 | 1/20 | 0.34 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14028811 | 0.83 | ADK (0.68) | ADKHIF1API4KAPI4K2BPI4K2A | |
| SCHEMBL4867832 | 0.83 | ADK (0.68) | ADKHIF1API4KAPI4K2BPI4K2A | |
| SCHEMBL14628001 | 0.76 | ADK (0.51) | ADKHIF1API4KAPI4K2BPI4K2A | |
| SCHEMBL13479945 | 0.73 | ADK (0.42) | ADKHIF1API4KAPI4K2BPI4K2A | |
| SCHEMBL9805215 | 0.73 | PI4KA (0.53) | ADKHIF1AGAAPI4KAPI4K2B | |
| SCHEMBL9805147 | 0.73 | PI4KA (0.53) | ADKHIF1AGAAPI4KAPI4K2B | |
| SCHEMBL18519939 | 0.72 | ADK (0.39) | ADK | |
| SCHEMBL20058638 | 0.72 | ADK (0.39) | ADKADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL12658366 | 0.71 | ADORA2A (0.48) | ADKADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL9805237 | 0.70 | ADK (0.65) | ADKHIF1API4KAPI4K2BPI4K2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019175260-A2 | MODIFIED OLIGONUCLEOTIDES AND METHODS OF USE IN TAUOPATHIES | JANSSEN PHARMACEUTICA NV (BE) | 2019-09-19 | — | — | WO | disclosed |