Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 3/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.30 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.30 |
| ▸ | PI4KA | P42356 | 1/20 | 0.30 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.30 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.30 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22083396 | 0.77 | — | — | |
| SCHEMBL21451310 | 0.72 | ADORA2A (0.36) | ADORA2AADORA1ADORA2BPI4KAPI4K2B | |
| SCHEMBL18526387 | 0.61 | NCF1 (0.32) | — | |
| SCHEMBL23675955 | 0.60 | ADORA2A (0.36) | ADORA2AADORA1ADORA2BPI4KAPI4K2B | |
| SCHEMBL21539238 | 0.59 | PI4KB (0.41) | ADORA2AADORA1ADORA2BPI4KAPI4K2B | |
| SCHEMBL21539360 | 0.59 | ADORA2A (0.71) | ADORA2AADORA1ADORA2BPI4KAPI4K2B | |
| SCHEMBL22300665 | 0.59 | ADORA2A (0.71) | ADORA2AADORA1ADORA2BPI4KAPI4K2B | |
| SCHEMBL14580328 | 0.57 | KDM4E (0.35) | ADORA2AADORA1ADORA2BPI4KAPI4K2B | |
| SCHEMBL20558598 | 0.57 | ADORA2A (0.52) | ADORA2AADORA1ADORA2BPI4KAPI4K2B | |
| SCHEMBL17690045 | 0.56 | DGAT1 (0.35) | ADORA2AADORA1ADORA2BPI4KAPI4K2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017027646-A1 | CYCLIC DI-NUCLEOTIDE COMPOUNDS AS STING AGONISTS | MERCK SHARP & DOHME CORP. (US) | 2017-02-16 | — | — | WO | disclosed |