Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 2/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15444076 | 0.80 | — | — | |
| SCHEMBL17717997 | 0.80 | CHRM5 (0.53) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| SCHEMBL10291428 | 0.78 | — | — | |
| SCHEMBL19669169 | 0.78 | CHRM2 (0.31) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| SCHEMBL12000751 | 0.78 | PDK1 (0.31) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| SCHEMBL12000752 | 0.78 | — | — | |
| SCHEMBL18519935 | 0.78 | CHRM2 (0.31) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| SCHEMBL17226048 | 0.74 | PDK1 (0.38) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| SCHEMBL13871548 | 0.73 | — | — | |
| SCHEMBL23760792 | 0.72 | FBP1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017027646-A1 | CYCLIC DI-NUCLEOTIDE COMPOUNDS AS STING AGONISTS | MERCK SHARP & DOHME CORP. (US) | 2017-02-16 | — | — | WO | disclosed |