Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 8/20 | 0.56 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.45 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1858690 | 0.90 | GPR52 (0.48) | GPR52NR4A2MRGPRX4PTGER1MTNR1A | |
| SCHEMBL3198140 | 0.86 | GPR52 (0.77) | GPR52MRGPRX4 | |
| SCHEMBL1850060 | 0.85 | GPR52 (0.76) | GPR52NR4A2MRGPRX4PTGER1PTGDR2 | |
| SCHEMBL3219273 | 0.83 | GPR52 (0.63) | GPR52 | |
| SCHEMBL1851338 | 0.81 | GPR52 (0.69) | GPR52NR4A2MRGPRX4PTGER1PTGDR2 | |
| SCHEMBL1847900 | 0.80 | GPR52 (0.75) | GPR52NR4A2MRGPRX4PLA2G2AKDM4C | |
| SCHEMBL1855792 | 0.79 | GPR52 (0.51) | GPR52NR4A2MRGPRX4KDM4C | |
| SCHEMBL1848567 | 0.77 | ALOX5 (0.56) | GPR52MTNR1AMTNR1B | |
| SCHEMBL1858056 | 0.77 | GPR52 (0.65) | GPR52NR4A2MRGPRX4PTGER1PLA2G2A | |
| SCHEMBL1849964 | 0.76 | GPR52 (0.75) | GPR52NR4A2MRGPRX4PLA2G2AKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2323978-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2011-05-25 | — | — | EP | disclosed |
| WO-2010018874-A1 | AMIDE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-02-18 | — | — | WO | disclosed |
| US-20100041891-A1 | AMIDE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100041891-A1 | AMIDE COMPOUND | GPR52, GPR132, NR5A2 | GPR52 1/4885NR4A2 8/4885MRGPRX4 287/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.