Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.41 |
| ▸ | ADK | P55263 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | NPY1R | P25929 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPY2R | P49146 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18510880 | 0.93 | ADORA3 (0.38) | ALDH1A1HIF1AADORA1ADORA3ADORA2A | |
| SCHEMBL6421558 | 0.87 | ADORA1 (0.50) | ALDH1A1ADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL24687189 | 0.87 | ADORA1 (0.50) | ALDH1A1ADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL15953489 | 0.86 | ADORA1 (0.56) | ALDH1A1HIF1AADORA1ADORA3ADORA2A | |
| SCHEMBL25496497 | 0.86 | ADORA1 (0.56) | ALDH1A1HIF1AADORA1ADORA3ADORA2A | |
| SCHEMBL15953492 | 0.86 | ADORA1 (0.56) | ALDH1A1HIF1AADORA1ADORA3ADORA2A | |
| SCHEMBL18490487 | 0.83 | ADORA1 (0.45) | ALDH1A1ADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL20782879 | 0.81 | ALDH1A1 (0.64) | ALDH1A1HIF1AADORA1ADORA3ADORA2A | |
| SCHEMBL25496518 | 0.79 | P2RY12 (0.52) | ADORA1ADORA3ADORA2AADORA2BP2RY12 | |
| SCHEMBL25496470 | 0.79 | ADORA1 (0.49) | ALDH1A1HIF1AADORA1ADORA3ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170044206-A1 | CYCLIC DI-NUCLEOTIDE COMPOUNDS AS STING AGONISTS | MERCK SHARP & DOHME CORP. (US) | 2017-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170044206-A1 | CYCLIC DI-NUCLEOTIDE COMPOUNDS AS STING AGONISTS | STING1, CGAS, IFNAR1 | ALDH1A1 4183/4885HIF1A 2562/4885ADORA1 32/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.