Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 6/20 | 0.50 |
| ▸ | ADK | P55263 | 6/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | SLC29A1 | Q99808 | 2/20 | 0.50 |
| ▸ | ADA | P00813 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | NPY1R | P25929 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NPY2R | P49146 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24687189 | 1.00 | ADORA1 (0.50) | ADORA1ADKLMNASLC29A1ADA | |
| SCHEMBL18490487 | 0.92 | ADORA1 (0.45) | ADORA1ADKLMNASLC29A1ALDH1A1 | |
| SCHEMBL18522117 | 0.87 | ALDH1A1 (0.42) | ADORA1ADKLMNASLC29A1ALDH1A1 | |
| SCHEMBL13396431 | 0.84 | PI4KA (0.45) | ADORA1SLC29A1ADORA3ADORA2AADORA2B | |
| SCHEMBL3314735 | 0.84 | PI4KA (0.45) | ADORA1SLC29A1ADORA3ADORA2AADORA2B | |
| SCHEMBL17301042 | 0.83 | LMNA (0.72) | ADORA1LMNASLC29A1ALDH1A1GLA | |
| SCHEMBL17889837 | 0.83 | LMNA (0.72) | ADORA1LMNASLC29A1ALDH1A1GLA | |
| SCHEMBL21953578 | 0.83 | LMNA (0.72) | ADORA1LMNASLC29A1ALDH1A1GLA | |
| SCHEMBL6909853 | 0.83 | LMNA (0.72) | ADORA1LMNASLC29A1ALDH1A1GLA | |
| SCHEMBL233209 | 0.83 | LMNA (0.72) | ADORA1LMNASLC29A1ALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018198084-A1 | CYCLIC DI-NUCLEOTIDE COMPOUNDS WITH TRICYCLIC NUCLEOBASES | LUPIN LIMITED (IN) | 2018-11-01 | — | — | WO | disclosed |
| EP-1589028-A2 | Modified oligonucleotides, their preparation and their use | Aventis Pharma Deutschland GmbH (DE) | 2005-10-26 | — | — | EP | disclosed |
| EP-0680969-B1 | Modified oligonucleotides, their preparation and their use | AVENTIS PHARMA GMBH (DE) | 2005-07-27 | — | — | EP | disclosed |
| US-6066720-A | WITH AT LEAST ONE 8-AZAPURINE BASE; FORMS MORE STABLE HYBRIDIZATION COMPLEXES WITH NUCLEIC ACIDS; FOR ANTISENSE AGENTS, DIAGNOSTIC AGENTS, PROBES, PRIMERS | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-05-23 | — | — | US | disclosed |
| EP-0680969-A2 | Modified oligonucleotides, their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-11-08 | — | — | EP | disclosed |