Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.69 |
| ▸ | HTT | P42858 | 2/20 | 0.69 |
| ▸ | HPGD | P15428 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.69 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | RAD52 | P43351 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29378504 | 0.91 | ALDH1A1 (0.67) | ALDH1A1HTTHPGDSMN1; SMN2PTGDR2 | |
| SCHEMBL637756 | 0.89 | ALDH1A1 (0.59) | ALDH1A1HTTHPGDSMN1; SMN2PTGDR2 | |
| SCHEMBL10573482 | 0.86 | ALDH1A1 (0.65) | ALDH1A1HTTHPGDSMN1; SMN2PTGDR2 | |
| SCHEMBL4808585 | 0.85 | ALDH1A1 (0.62) | ALDH1A1HTTHPGDSMN1; SMN2PTGDR2 | |
| SCHEMBL271619 | 0.84 | ALDH1A1 (0.66) | ALDH1A1HTTHPGDSMN1; SMN2PTGDR2 | |
| SCHEMBL28639293 | 0.83 | ALDH1A1 (0.47) | ALDH1A1HTTHPGDSMN1; SMN2PTGDR2 | |
| SCHEMBL21410036 | 0.83 | ALDH1A1 (0.61) | ALDH1A1HTTHPGDSMN1; SMN2PTGDR2 | |
| 1,2-Diisopentoxybenzene SCHEMBL2843498 | 0.82 | HTT (0.62) | ALDH1A1HTTSMN1; SMN2MAPTLMNA | |
| SCHEMBL6914412 | 0.82 | ALDH1A1 (1.00) | ALDH1A1HTTHPGDSMN1; SMN2PTGDR2 | |
| SCHEMBL5661861 | 0.82 | ALDH1A1 (0.46) | ALDH1A1HTTHPGDSMN1; SMN2PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117624047-B | Antitumor compound | Beijing Keyou Ai Technology Co.,Ltd. (CN) | 2026-05-26 | — | — | CN | disclosed |
| US-20250326744-A1 | PIPERAZINE DERIVATIVE OR SALT THEREOF, AND PHARMACEUTICAL COMPOSITION | FUJIFILM CORPORATION (JP) | 2025-10-23 | — | — | US | disclosed |
| CN-119816484-A | Novel piperazine derivative or salt thereof and pharmaceutical composition | 富士胶片株式会社 | 2025-04-11 | — | — | CN | disclosed |
| CN-117624047-A | Antitumor compound | 北京科佑爱科技有限责任公司 | 2024-03-01 | — | — | CN | disclosed |
| WO-2024043334-A1 | NOVEL PIPERAZINE DERIVATIVE OR SALT THEREOF AND PHARMACEUTICAL COMPOSITION | 富士フイルム株式会社 | 2024-02-29 | — | — | WO | disclosed |
| CN-113582988-A | Pyridinocyclic compound and medical application thereof | 正大天晴药业集团股份有限公司 | 2021-11-02 | — | — | CN | disclosed |
| EP-2097419-B1 | BENZOFUROPYRIMIDINONES AS PROTEIN KINASE INHIBITORS | EXELIXIS INC (US) | 2011-05-25 | — | — | EP | disclosed |
| CN-101965351-A | Benzofuran pyrimidinones | EXELIXIS INC | 2011-02-02 | — | — | CN | disclosed |
| US-20090247559-A1 | Benzofuropyrimidinones | EXELIXIS, INC. (US) | 2009-10-01 | — | — | US | disclosed |
| EP-2097419-A1 | BENZOFUROPYRIMIDINONES AS PROTEIN KINASE INHIBITORS | Exelixis, Inc. (US) | 2009-09-09 | — | — | EP | disclosed |
| WO-2009086264-A1 | BENZOFUROPYRIMIDINONES AS PROTEIN KINASE INHIBITORS | EXELIXIS, INC. (US) | 2009-07-09 | — | — | WO | disclosed |
| CN-1040549-C | Liquid hard surface detergent compositions containing zwitterionic and cationic detergent, surfactants and monoethanolamine and/or beta-aminoalkanol | PROCTER & GAMBLE (US) | 1998-11-04 | — | — | CN | disclosed |
| CN-1078745-A | The liquid hard surface detergent compositions that contains tensio-active agent and alkanolamine | PROCTER & GAMBLE (US) | 1993-11-24 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090247559-A1 | Benzofuropyrimidinones | F12, BRI3BP, BRD1 | ALDH1A1 315/4885HTT 1923/4885HPGD 2284/4885 |
| US-20250326744-A1 | PIPERAZINE DERIVATIVE OR SALT THEREOF, AND PHARMACEUTICAL COMPOSITION | ABCB11, ABCC1, SLC11A2 | ALDH1A1 774/4885HTT 1241/4885HPGD 1533/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.