Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28639114 | 0.86 | ALDH1A1 (0.41) | ALDH1A1HTTHPGDSMN1; SMN2TLR8 | |
| SCHEMBL30933880 | 0.84 | ALDH1A1 (0.50) | ALDH1A1HTTHPGDSMN1; SMN2MAPT | |
| SCHEMBL1852272 | 0.83 | ALDH1A1 (0.69) | ALDH1A1HTTHPGDSMN1; SMN2TLR8 | |
| SCHEMBL23148080 | 0.83 | ALDH1A1 (0.53) | ALDH1A1HTTHPGDSMN1; SMN2MAPT | |
| SCHEMBL13191450 | 0.83 | ALDH1A1 (0.49) | ALDH1A1HTTHPGDSMN1; SMN2MAPT | |
| SCHEMBL28646030 | 0.81 | ALDH1A1 (0.47) | ALDH1A1HTTHPGDSMN1; SMN2MAPT | |
| SCHEMBL22809689 | 0.81 | SCN8A (0.48) | ALDH1A1HTTHPGDSMN1; SMN2TLR8 | |
| SCHEMBL1881661 | 0.80 | LMNA (0.50) | ALDH1A1HTTHPGDSMN1; SMN2MAPT | |
| SCHEMBL26022705 | 0.80 | ALDH1A1 (0.50) | ALDH1A1HTTHPGDSMN1; SMN2MAPT | |
| SCHEMBL10385008 | 0.80 | ALDH1A1 (0.46) | ALDH1A1HTTHPGDSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113582988-A | Pyridinocyclic compound and medical application thereof | 正大天晴药业集团股份有限公司 | 2021-11-02 | — | — | CN | disclosed |