Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | FABP3 | P05413 | 1/20 | 0.44 |
| ▸ | FABP4 | P15090 | 1/20 | 0.44 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.44 |
| ▸ | SERPINE1 | P05121 | 3/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4906903 | 0.86 | GAA (0.52) | ALDH1A1HSD17B10LMNAGAASERPINE1 | |
| SCHEMBL22908991 | 0.84 | RORC (0.51) | ALDH1A1HSD17B10KDM4EHPGDLMNA | |
| SCHEMBL27602783 | 0.83 | ALDH1A1 (0.43) | ALDH1A1HSD17B10LMNAGAASERPINE1 | |
| SCHEMBL13624547 | 0.81 | FABP3 (0.44) | ALDH1A1HSD17B10KDM4EHPGDLMNA | |
| SCHEMBL15613397 | 0.81 | GABRA1 (0.52) | ALDH1A1HSD17B10KDM4EHPGDGAA | |
| SCHEMBL17417188 | 0.81 | HTT (0.54) | ALDH1A1HSD17B10KDM4EHPGDLMNA | |
| SCHEMBL5150398 | 0.80 | GAA (0.47) | ALDH1A1LMNAGAAHSP90AA1HSP90AB1 | |
| SCHEMBL8365957 | 0.80 | TYR (0.49) | ALDH1A1HSD17B10KDM4EHPGDLMNA | |
| SCHEMBL7978251 | 0.79 | ALDH1A1 (0.52) | ALDH1A1HSD17B10KDM4ELMNAGAA | |
| SCHEMBL8496152 | 0.79 | ALDH1A1 (0.50) | ALDH1A1KDM4EHPGDLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3334464-B1 | MANGANESE-BASED CHELATE CONJUGATES FOR MOLECULAR MR IMAGING | MASSACHUSETTS GEN HOSPITAL (US) | 2024-04-10 | — | — | EP | disclosed |
| US-20210015948-A1 | MANGANESE-BASED CHELATE CONJUGATES FOR MOLECULAR MR IMAGING | THE GENERAL HOSPITAL CORPORATION | 2021-01-21 | — | — | US | disclosed |
| US-10835623-B2 | Manganese-based chelate conjugates for molecular MR imaging | THE GENERAL HOSPITAL CORPORATION (US) | 2020-11-17 | — | — | US | disclosed |
| US-20190001003-A1 | MANGANESE-BASED CHELATE CONJUGATES FOR MOLECULAR MR IMAGING | THE GENERAL HOSPITAL CORPORATION | 2019-01-03 | — | — | US | disclosed |
| WO-2017027834-A1 | MANGANESE-BASED CHELATE CONJUGATES FOR MOLECULAR MR IMAGING | THE GENERAL HOSPITAL CORPORATION (US) | 2017-02-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210015948-A1 | MANGANESE-BASED CHELATE CONJUGATES FOR MOLECULAR MR IMAGING | MPI, MAG, MNS1 | ALDH1A1 4356/4885HSD17B10 4727/4885KDM4E 2716/4885 |
| US-20190001003-A1 | MANGANESE-BASED CHELATE CONJUGATES FOR MOLECULAR MR IMAGING | MPI, MAG, MNS1 | ALDH1A1 4356/4885HSD17B10 4727/4885KDM4E 2716/4885 |
| US-10835623-B2 | Manganese-based chelate conjugates for molecular MR imaging | MPI, MAG, MNS1 | ALDH1A1 4356/4885HSD17B10 4727/4885KDM4E 2716/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.