Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.50 |
| ▸ | ERN1 | O75460 | 2/20 | 0.47 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | TNKS | O95271 | 1/20 | 0.37 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16015010 | 0.91 | ACHE (0.48) | ACHEERN1TNKS2ALDH1A1CYP3A4 | |
| SCHEMBL890499 | 0.89 | ACHE (0.55) | ACHEERN1TNKS2ALDH1A1CYP3A4 | |
| SCHEMBL7520392 | 0.88 | ERN1 (0.57) | ACHEERN1TNKS2ALDH1A1ALOX5 | |
| SCHEMBL18523538 | 0.88 | ERN1 (0.51) | ERN1ALDH1A1CYP3A4KDM4EGAA | |
| SCHEMBL16014627 | 0.87 | ACHE (0.48) | ACHEERN1TNKS2ALDH1A1CYP3A4 | |
| SCHEMBL9938324 | 0.84 | ACHE (0.68) | ACHEALDH1A1CYP3A4MEN1MAPT | |
| SCHEMBL890444 | 0.83 | ERN1 (0.49) | ACHEERN1TNKS2ALDH1A1CYP3A4 | |
| SCHEMBL11950304 | 0.82 | ACHE (0.56) | ACHEALDH1A1CYP3A4ESR1ESR2 | |
| SCHEMBL16024748 | 0.81 | ERN1 (0.50) | ACHEERN1TNKS2ALDH1A1ALOX5 | |
| SCHEMBL16015052 | 0.81 | ESR2 (0.47) | ACHEERN1TNKS2ALOX5PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10131607-B2 | Process for preparing unsymmetric OCO pincer ligands from the group of the M-terphenyl compounds | EVONIK DEGUSSA GMBH (DE) | 2018-11-20 | — | — | US | disclosed |
| US-20170050910-A1 | PROCESS FOR PREPARING UNSYMMETRIC OCO PINCER LIGANDS FROM THE GROUP OF THE M-TERPHENYL COMPOUNDS | EVONIK DEGUSSA GMBH (DE) | 2017-02-23 | — | — | US | disclosed |
| US-20170050910-A1 | PROCESS FOR PREPARING UNSYMMETRIC OCO PINCER LIGANDS FROM THE GROUP OF THE M-TERPHENYL COMPOUNDS | EVONIK DEGUSSA GMBH (DE) | 2017-02-23 | — | — | US | disclosed |
| US-20170050910-A1 | PROCESS FOR PREPARING UNSYMMETRIC OCO PINCER LIGANDS FROM THE GROUP OF THE M-TERPHENYL COMPOUNDS | EVONIK DEGUSSA GMBH (DE) | 2017-02-23 | — | — | US | disclosed |
| EP-3133189-A1 | METHOD FOR THE PREPARATION OF ASYMMETRIC OCO PINCER LIGANDS FROM THE GROUP OF M TERPHENYL COMPOUNDS | Evonik Degussa GmbH (DE) | 2017-02-22 | — | — | EP | disclosed |
| EP-3133189-A1 | METHOD FOR THE PREPARATION OF ASYMMETRIC OCO PINCER LIGANDS FROM THE GROUP OF M TERPHENYL COMPOUNDS | Evonik Degussa GmbH (DE) | 2017-02-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10131607-B2 | Process for preparing unsymmetric OCO pincer ligands from the group of the M-terphenyl compounds | COMT, MSMO1, TYR | ACHE 773/4885ERN1 4109/4885TNKS2 1049/4885 |
| US-20170050910-A1 | PROCESS FOR PREPARING UNSYMMETRIC OCO PINCER LIGANDS FROM THE GROUP OF THE M-TERPHENYL COMPOUNDS | COMT, MSMO1, TYR | ACHE 773/4885ERN1 4109/4885TNKS2 1049/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.