SCHEMBL7520392

SCHEMBL7520392

COc1cc(C)cc(-c2cc(C)cc(OC)c2O)c1O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 1/20 0.57
ACHE P22303 2/20 0.52
TNKS2 Q9H2K2 3/20 0.50
PTGS2 P35354 2/20 0.48
ALOX5 P09917 1/20 0.48
GAA P10253 2/20 0.43
MAPT P10636 2/20 0.43
KMT2A Q03164 2/20 0.43
ALDH1A1 P00352 2/20 0.43
KDM4E B2RXH2 1/20 0.43
POLB P06746 1/20 0.43
APEX1 P27695 1/20 0.43
MPI P34949 1/20 0.43
RECQL P46063 1/20 0.43
CA12 O43570 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA3 P07451 1/20 0.43
PKM P14618 1/20 0.43
CA4 P22748 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16024748 0.92 ERN1 (0.50) ERN1ACHETNKS2PTGS2ALOX5
SCHEMBL890444 0.90 ERN1 (0.49) ERN1ACHETNKS2PTGS2ALOX5
SCHEMBL16091526 0.90 ACHE (0.59) ERN1ACHETNKS2PTGS2ALOX5
SCHEMBL18523530 0.88 ACHE (0.50) ERN1ACHETNKS2PTGS2ALOX5
SCHEMBL890499 0.88 ACHE (0.55) ERN1ACHETNKS2PTGS2ALOX5
SCHEMBL562147 0.87 ERN1 (0.63) ERN1ACHEPTGS2ALOX5GAA
SCHEMBL24740979 0.87 MAPT (0.52) ERN1ACHETNKS2MAPTKMT2A
SCHEMBL16014627 0.87 ACHE (0.48) ERN1ACHETNKS2GAAMAPT
SCHEMBL16024745 0.87 ERN1 (0.46) ERN1ACHETNKS2PTGS2ALOX5
SCHEMBL18525393 0.87 ERN1 (0.46) ERN1ACHETNKS2PTGS2ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230357802-A1 CONVERSION OF LIGNIN INTO BIOPLASTICS AND LIPID FUELS TEXAS A & M UNIV SYS (US) 2023-11-09 US disclosed
US-10287237-B1 Polymeric materials made from vanillin THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2019-05-14 US disclosed
US-20190032098-A1 PROCESS FOR PREPARING BIPHENYL COMPOUNDS UNIV BORDEAUX (FR) 2019-01-31 US disclosed
US-9815775-B1 Polymeric materials made from vanillin THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2017-11-14 US disclosed
US-9815775-B1 Polymeric materials made from vanillin THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2017-11-14 US disclosed
US-20170240937-A1 NEW PROCESS FOR PREPARING BIPHENYL COMPOUNDS UNIVERSITÉ DE BORDEAUX (FR) 2017-08-24 US disclosed
US-20170240937-A1 NEW PROCESS FOR PREPARING BIPHENYL COMPOUNDS UNIVERSITÉ DE BORDEAUX (FR) 2017-08-24 US disclosed
US-20170137446-A1 METHOD OF PREPARING AROMATIC COMPOUNDS FROM LIGNIN COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2017-05-18 US disclosed
US-9353219-B1 Polymeric materials made from vanillin THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2016-05-31 US disclosed
US-9353219-B1 Polymeric materials made from vanillin THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2016-05-31 US disclosed
US-20090044294-A1 Method for modifying lignin composition and increasing in vivo digestibility of forages NOBLE RESEARCH INSTITUTE, LLC 2009-02-12 US disclosed
US-20090044294-A1 Method for modifying lignin composition and increasing in vivo digestibility of forages NOBLE RESEARCH INSTITUTE, LLC 2009-02-12 US disclosed
EP-0888364-B1 Process to prepare a multidentate phosphite compound DSM NV (NL) 2002-02-06 EP disclosed
JP-2000143446-A MAKEUP COSMETIC KANEBO LTD 2000-05-23 JP disclosed
US-5910600-A Bisphosphite compound, process for its production and hydroformylation process employing the bisphosphite compound MITSUBISHI CHEMICAL CORPORATION (JP) 1999-06-08 US disclosed
US-5710306-A REACTING A PHOSPHPHOROCHLORODITE WITH HYDOXY COMPOUND CONTAINING FUSED RING AND HYDROHALOGENATION DSM N.V. (NL) 1998-01-20 US disclosed
EP-0518241-B1 Hydroformylation process and bisphosphite compound used therein MITSUBISHI CHEM CORP (JP) 1996-09-11 EP disclosed
US-5391801-A Used to form respective aldehyde by reacting olefinic compound with carbon monoxide and hydrogen in presence of group 8 metal catalyst MITSUBISHI KASEI CORPORATION (JP) 1995-02-21 US disclosed
US-5235113-A Reacting olefin with hydrogen and carbon monoxide in the presence of a group 8 metal catalyst and a phosphite compound MITSUBISHI KASEI CORPORATION (JP) 1993-08-10 US disclosed
EP-0518241-A2 Hydroformylation process and bisphosphite compound used therein Mitsubishi Chemical Corporation (JP) 1992-12-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190032098-A1 PROCESS FOR PREPARING BIPHENYL COMPOUNDS CYP1B1, CYP1A1, CYP1A2 ERN1 3271/4885ACHE 286/4885TNKS2 3511/4885
US-10287237-B1 Polymeric materials made from vanillin VCL, PORCN, HVCN1 ERN1 4093/4885ACHE 1761/4885TNKS2 2082/4885
US-20170240937-A1 NEW PROCESS FOR PREPARING BIPHENYL COMPOUNDS CYP1B1, CYP1A1, CYP1A2 ERN1 3495/4885ACHE 444/4885TNKS2 3352/4885
US-20170137446-A1 METHOD OF PREPARING AROMATIC COMPOUNDS FROM LIGNIN DDT, PAH, PNPO ERN1 4445/4885ACHE 18/4885TNKS2 3962/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.