Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1764441 | 0.80 | HRH3 (0.51) | HRH3CHRNA7 | |
| SCHEMBL4290379 | 0.76 | HRH3 (0.51) | HRH3OPRM1OPRK1OPRD1CHRNA7 | |
| SCHEMBL18751630 | 0.76 | CHRNB2 (0.50) | HRH3OPRM1OPRK1OPRL1OPRD1 | |
| SCHEMBL18751629 | 0.76 | SLC18A3 (0.51) | HRH3OPRM1OPRK1OPRL1OPRD1 | |
| SCHEMBL10770079 | 0.76 | CHRNB2 (0.50) | HRH3OPRM1OPRK1OPRL1OPRD1 | |
| SCHEMBL1989282 | 0.76 | SLC18A3 (0.51) | HRH3OPRM1OPRK1OPRL1OPRD1 | |
| SCHEMBL10770146 | 0.76 | ALDH1A1 (0.50) | HRH3CHRNA7 | |
| Hydrochloric Acid SCHEMBL28558595 | 0.74 | SLC18A3 (0.50) | HRH3OPRM1OPRK1OPRL1OPRD1 | |
| Hydrochloric Acid SCHEMBL10764868 | 0.74 | HRH3 (0.49) | HRH3OPRM1OPRK1OPRL1OPRD1 | |
| SCHEMBL9153287 | 0.74 | CHRNB2 (0.52) | HRH3OPRM1OPRK1OPRL1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2712000-B1 | Materials for Organic Electroluminescent Devices | MERCK PATENT GMBH (DE) | 2017-02-15 | — | — | EP | disclosed |