Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.51 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.50 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.50 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.50 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.50 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.45 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.43 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.43 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.43 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.43 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.43 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18751629 | 1.00 | SLC18A3 (0.51) | SLC18A3CHRNB2CHRNB4CHRNA3CHRNA7 | |
| Hydrochloric Acid SCHEMBL28558595 | 0.98 | SLC18A3 (0.50) | SLC18A3CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL9153287 | 0.98 | CHRNB2 (0.52) | SLC18A3CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL18751630 | 0.96 | CHRNB2 (0.50) | SLC18A3CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL9153176 | 0.96 | CHRNB2 (0.55) | SLC18A3CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL10770079 | 0.96 | CHRNB2 (0.50) | SLC18A3CHRNB2CHRNB4CHRNA3CHRNA7 | |
| Hydrochloric Acid SCHEMBL10764868 | 0.95 | HRH3 (0.49) | SLC18A3CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL17114372 | 0.94 | CHRNB2 (0.52) | SLC18A3CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL13660506 | 0.93 | HRH3 (0.57) | SLC18A3CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL13660513 | 0.91 | CHRNB2 (0.56) | SLC18A3CHRNB2CHRNB4CHRNA3CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250224340-A1 | Colorimetric Detection of Organic Amines Using Metal-Organic Frameworks | THE JOHNS HOPKINS UNIVERSITY | 2025-07-10 | — | — | US | claimed |
| CN-114137233-A | Quantitative detection test strip, kit and method for phencyclidine | 佛山墨赛生物技术有限公司 | 2022-03-04 | — | — | CN | claimed |
| WO-2011091418-A1 | SCREENING METHOD FOR ADVERSE SIDE EFFECTS OF A THERAPEUTIC PHARMACEUTICAL DRUG | NORTHEASTERN UNIVERSITY (US) | 2011-07-28 | — | — | WO | claimed |
| EP-4362926-A1 | MODIFIED RELEASE FORMULATIONS OF METHADONE AND ITS ISOMERS, ESMETHADONE AND LEVOMETHADONE AND DERIVATIVES | Manfredi, Paolo L. (US) | 2024-05-08 | — | — | EP | disclosed |
| CN-117999071-A | Modified release formulations of methadone and its isomers, esomeprazole and levomethadone and derivatives | 保罗·L·曼佛雷蒂 | 2024-05-07 | — | — | CN | disclosed |
| US-20240122878-A1 | MODIFIED RELEASE FORMULATIONS OF METHADONE AND ITS ISOMERS, ESMETHADONE AND LEVOMETHADONE AND DERIVATIVES | MANFREDI PAOLO L (US) | 2024-04-18 | — | — | US | disclosed |
| US-20240115203-A1 | SWEAT PATCH WITH IMPROVED ADHESION AND ANTI-TAMPERING FEATURE(S) | Smart Sales, LLC dba Smartox | 2024-04-11 | — | — | US | disclosed |
| US-11754560-B2 | Apparatus for collecting and detecting an analyte in a fluid sample | Healgen Scientific Limited (US) | 2023-09-12 | — | — | US | disclosed |
| US-11730744-B2 | Methods of reducing risk of preterm birth | COVIS PHARMA GMBH (CH) | 2023-08-22 | — | — | US | disclosed |
| WO-2023278400-A1 | MODIFIED RELEASE FORMULATIONS OF METHADONE AND ITS ISOMERS, ESMETHADONE AND LEVOMETHADONE AND DERIVATIVES | UNIVERSITY OF PADOVA (IT) | 2023-01-05 | — | — | WO | disclosed |
| US-11304962-B2 | Methods of reducing risk of preterm birth | COVIS PHARMA GMBH (CH) | 2022-04-19 | — | — | US | disclosed |
| US-20080269202-A1 | Novel 2,3-benzodiazepine derivatives and their use as antipsychotic agents | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2008-10-30 | — | — | US | disclosed |
| WO-2008124075-A1 | NOVEL 2,3-BENZODIAZEPINE DERIVATIVES AND THEIR USE AS ANTIPSYCHOTIC AGENTS | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2008-10-16 | — | — | WO | disclosed |
| CN-101052393-A | Novel polymorphs of azabicyclohexane | DOV PHARMACEUTICAL INC (US) | 2007-10-10 | — | — | CN | disclosed |
| EP-1786417-A2 | NOVEL POLYMORPHS OF AZABICYCLOHEXANE | DOV Pharmaceutical, Inc. (US) | 2007-05-23 | — | — | EP | disclosed |
| US-20070043100-A1 | Novel polymorphs of azabicyclohexane | ETHISMOS RESEARCH, INC. | 2007-02-22 | — | — | US | disclosed |
| WO-2006023659-A2 | NOVEL POLYMORPHS OF AZABICYCLOHEXANE | DOV PHARMACEUTICAL, INC. (US) | 2006-03-02 | — | — | WO | disclosed |
| WO-1989001160-A1 | NEW BIFUNCTIONAL PHOTOEXCITABLE REAGENTS, THEIR PREPARATION AND USE, IN PARTICULAR FOR PHOTOAFFINITY LABELLING | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS (FR) | 1989-02-09 | — | — | WO | disclosed |
| US-4118393-A | Phenyl azabicyclohexanones | AMERICAN CYANAMID COMPANY (US) | 1978-10-03 | — | — | US | disclosed |
| US-4118417-A | Process for resolving cis-1-substituted phenyl-1,2-cyclopropanedicarboxylic acids | AMERICAN CYANAMID COMPANY (US) | 1978-10-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080269202-A1 | Novel 2,3-benzodiazepine derivatives and their use as antipsychotic agents | GABRA3, GABRB3, GABRA4 | SLC18A3 189/4885CHRNB2 78/4885CHRNB4 88/4885 |
| US-20070043100-A1 | Novel polymorphs of azabicyclohexane | CYP3A43, CYP2D6, CYP26B1 | SLC18A3 2878/4885CHRNB2 2852/4885CHRNB4 2697/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.