⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29826847 | 1.00 | — | — | |
| SCHEMBL12496522 | 0.83 | CHEK1 (0.49) | — | |
| SCHEMBL12634621 | 0.80 | SLC22A12 (0.45) | — | |
| SCHEMBL4788868 | 0.76 | — | — | |
| SCHEMBL14634341 | 0.76 | — | — | |
| SCHEMBL21503566 | 0.74 | MAOB (0.51) | — | |
| SCHEMBL12630708 | 0.73 | CHEK1 (0.51) | — | |
| SCHEMBL1026572 | 0.73 | ALDH1A1 (0.48) | — | |
| SCHEMBL14153105 | 0.73 | GABRG2 (0.48) | — | |
| SCHEMBL22031532 | 0.73 | GRM5 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 811 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117199519-A | Electrolyte, preparation method and application thereof, and lithium battery | 北京纳米能源与系统研究所 | 2023-12-08 | — | — | CN | claimed |
| CN-116375549-A | Method and system for synthesizing amide compound from nitrile compound | 深圳湾实验室 | 2023-07-04 | — | — | CN | claimed |
| CN-111302968-B | Synthesis method of amide nitrogen trifluoromethyl compound | 中国科学院上海有机化学研究所 | 2021-06-08 | — | — | CN | claimed |
| US-10889567-B2 | Pyridin-2(1H)-one quinolinone derivatives as mutant-isocitrate dehydrogenase inhibitors | FORMA THERAPEUTICS, INC. (US) | 2021-01-12 | — | — | US | claimed |
| US-20200223822-A1 | PYRIDIN-2(1H)-ONE QUINOLINONE DERIVATIVES AS MUTANT-ISOCITRATE DEHYDROGENASE INHIBITORS | FORMA TM2, INC. | 2020-07-16 | — | — | US | claimed |
| CN-111302968-A | Synthesis method of amide nitrogen trifluoromethyl compound | 中国科学院上海有机化学研究所 | 2020-06-19 | — | — | CN | claimed |
| US-10550098-B2 | Pyridin-2(1H)-one quinolinone derivatives as mutant-isocitrate dehydrogenase inhibitors | FORMA THERAPEUTICS, INC. (US) | 2020-02-04 | — | — | US | claimed |
| US-20190263778-A1 | PYRIDIN-2(1H)-ONE QUINOLINONE DERIVATIVES AS MUTANT-ISOCITRATE DEHYDROGENASE INHIBITORS | FORMA THERAPEUTICS, INC. | 2019-08-29 | — | — | US | claimed |
| WO-2008054284-A1 | A NEW PROCESS FOR THE PRODUCTION OF 5-FLUORO-PYRIDINE-2- CARBONITRILE AND 5-FLUORO-N-HYDROXY-PYRIDINE-2- CARBOXAMIDINE. | ASTRAZENECA AB (SE) | 2008-05-08 | — | — | WO | claimed |
| US-20070255061-A1 | 5-Fluoro-, Chloro-and Cyano-Pyridin-2-Yl-Tetrazoles as Ligands of the Metabotropic Glutamate Receptor-5 | ASTRAZENECA AB (SE) | 2007-11-01 | — | — | US | claimed |
| JP-2007514790-A | — | — | 2007-06-07 | — | — | JP | claimed |
| CN-1906187-A | 5-fluoro-, chloro- and cyano-pyridin-2-yl-tetrazoles as ligands of the metabotropic glutamate receptor-5 | ASTRAZENECA AB (SE) | 2007-01-31 | — | — | CN | claimed |
| EP-1713791-A1 | 5-FLUORO-, CHLORO- AND CYANO-PYRIDIN-2-YL-TETRAZOLES AS LIGANDS OF THE METABOTROPIC GLUTAMATE RECEPTOR-5 | AstraZeneca AB (SE) | 2006-10-25 | — | — | EP | claimed |
| WO-2005066155-A1 | 5-FLUORO-, CHLORO- AND CYANO-PYRIDIN-2-YL-TETRAZOLES AS LIGANDS OF THE METABOTROPIC GLUTAMATE RECEPTOR-5 | ASTRAZENECA AB (SE) | 2005-07-21 | — | — | WO | claimed |
| EP-0951466-A2 | CYCLOALKYL, LACTAM, LACTONE AND RELATED COMPOUNDS, PHARMACEUTICAL COMPOSITIONS COMPRISING SAME, AND METHODS FOR INHIBITING BETA-AMYLOID PEPTIDE RELEASE AND/OR ITS SYNTHESIS BY USE OF SUCH COMPOUNDS | Elan Pharmaceuticals, Inc. (US) | 1999-10-27 | — | — | EP | claimed |
| WO-1998028268-A2 | CYCLOALKYL, LACTAM, LACTONE AND RELATED COMPOUNDS AS β-AMYLOID PEPTIDE RELEASE INHIBITORS | ELAN PHARMACEUTICALS, INC. (US) | 1998-07-02 | — | — | WO | claimed |
| EP-4747258-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS | Tenvie Therapeutics, Inc. (US) | 2026-05-27 | — | — | EP | disclosed |
| CN-122080069-A | Phospholipid compounds and uses thereof | — | 2026-05-26 | — | — | CN | disclosed |
| EP-1210344-A1 | HETEROPOLYCYCLIC COMPOUNDS AND THEIR USE AS METABOTROPIC GLUTAMATE RECEPTOR ANTAGONISTS | NPS PHARMACEUTICALS, INC. (US) | 2002-06-05 | — | — | EP | disclosed |
| WO-2001012627-A1 | HETEROPOLYCYCLIC COMPOUNDS AND THEIR USE AS METABOTROPIC GLUTAMATE RECEPTOR ANTAGONISTS | NPS PHARMACEUTICALS, INC. (US) | 2001-02-22 | — | — | WO | disclosed |