SCHEMBL18529337

SCHEMBL18529337

OCC(O)C(O)COCC(O)C(O)CO

nearest known ligand 0.60

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
TDP1 Q9NUW8 2/20 0.42
THRB P10828 1/20 0.33
ALDH1A1 P00352 1/20 0.33
TSHR P16473 1/20 0.32
MAPK1 P28482 1/20 0.32
KDM4E B2RXH2 2/20 0.31
PDE4A P27815 1/20 0.31
USP2 O75604 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL578416 1.00 LMNA (0.44) LMNAL3MBTL1TDP1THRBALDH1A1
SCHEMBL5599449 0.89 USP2 (0.43) LMNAL3MBTL1TDP1THRBALDH1A1
SCHEMBL4429401 0.89 USP2 (0.43) LMNAL3MBTL1TDP1THRBALDH1A1
SCHEMBL5158290 0.85 TSHR (0.47) LMNAL3MBTL1TDP1THRBALDH1A1
SCHEMBL7736939 0.85 TSHR (0.47) LMNAL3MBTL1TDP1THRBALDH1A1
SCHEMBL22289432 0.83 ALDH1A1 (0.43) LMNAL3MBTL1TDP1ALDH1A1TSHR
SCHEMBL15013779 0.83 ALDH1A1 (0.43) LMNAL3MBTL1TDP1ALDH1A1TSHR
SCHEMBL3904175 0.81 LMNA (0.56) LMNAL3MBTL1TDP1ALDH1A1KDM4E
SCHEMBL619757 0.81 LMNA (0.65) LMNAL3MBTL1TDP1ALDH1A1KDM4E
SCHEMBL3909140 0.81 LMNA (0.65) LMNAL3MBTL1TDP1ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10703929-B2 Aqueous polymer compositions comprising polyurethane (meth)acrylates BASF SE (DE) 2020-07-07 US disclosed
US-20180244948-A1 AQUEOUS POLYMER COMPOSITIONS COMPRISING POLYURETHANE (METH)ACRYLATES BASF SE (DE) 2018-08-30 US disclosed
EP-3337840-A1 AQUEOUS POLYMER COMPOSITIONS COMPRISING POLYURETHANE (METH)ACRYLATES BASF SE (DE) 2018-06-27 EP disclosed
WO-2017029280-A1 AQUEOUS POLYMER COMPOSITIONS COMPRISING POLYURETHANE (METH)ACRYLATES BASF SE (DE) 2017-02-23 WO disclosed