SCHEMBL578416

SCHEMBL578416

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nearest known ligand 0.60

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
TDP1 Q9NUW8 2/20 0.42
THRB P10828 1/20 0.33
ALDH1A1 P00352 1/20 0.33
TSHR P16473 1/20 0.32
MAPK1 P28482 1/20 0.32
KDM4E B2RXH2 2/20 0.31
PDE4A P27815 1/20 0.31
USP2 O75604 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18529337 1.00 LMNA (0.44) LMNAL3MBTL1TDP1THRBALDH1A1
SCHEMBL5599449 0.89 USP2 (0.43) LMNAL3MBTL1TDP1THRBALDH1A1
SCHEMBL4429401 0.89 USP2 (0.43) LMNAL3MBTL1TDP1THRBALDH1A1
SCHEMBL5158290 0.85 TSHR (0.47) LMNAL3MBTL1TDP1THRBALDH1A1
SCHEMBL7736939 0.85 TSHR (0.47) LMNAL3MBTL1TDP1THRBALDH1A1
SCHEMBL22289432 0.83 ALDH1A1 (0.43) LMNAL3MBTL1TDP1ALDH1A1TSHR
SCHEMBL15013779 0.83 ALDH1A1 (0.43) LMNAL3MBTL1TDP1ALDH1A1TSHR
SCHEMBL3904175 0.81 LMNA (0.56) LMNAL3MBTL1TDP1ALDH1A1KDM4E
SCHEMBL619757 0.81 LMNA (0.65) LMNAL3MBTL1TDP1ALDH1A1KDM4E
SCHEMBL3909140 0.81 LMNA (0.65) LMNAL3MBTL1TDP1ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 164 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0912546-A1 IMPROVED RESERVOIR COMPONENTS AUSTRALIAN MEMBRANE AND BIOTECHNOLOGY RESEARCH INSTITUTE (AU) 1999-05-06 EP claimed
WO-1997043274-A1 IMPROVED RESERVOIR COMPONENTS AUSTRALIAN MEMBRANE AND BIOTECHNOLOGY RESEARCH INSTITUTE (AU) 1997-11-20 WO claimed
WO-2024142849-A1 WATER-IN-OIL EMULSION COSMETIC COMPOSITION 株式会社 資生堂 2024-07-04 WO disclosed
CN-117159398-B Super-fluid compound sun-screening agent and oil-in-water-in-oil triple sun-screening emulsion 广州嘉瑞新材料有限公司 2024-05-31 CN disclosed
US-11964043-B2 Method of emulsification using core-corona type microparticles SHISEIDO COMPANY, LTD. (JP) 2024-04-23 US disclosed
US-11931448-B2 Water-in-oil type emulsion composition SHISEIDO COMPANY, LTD. (JP) 2024-03-19 US disclosed
CN-117500478-A Hair care composition comprising hydroxylated triglyceride oligomers 宝洁公司 2024-02-02 CN disclosed
CN-117460490-A Skin external composition containing taurine crystal with useful component 考司美德制药株式会社 2024-01-26 CN disclosed
CN-117377454-A Skin care composition 考司美德制药株式会社 2024-01-09 CN disclosed
EP-3520772-B1 COSMETIC RAW MATERIAL USING CORE-CORONA TYPE MICROPARTICLES AND OIL-IN-WATER TYPE EMULSION COSMETIC SHISEIDO CO LTD (JP) 2023-12-20 EP disclosed
CN-117159398-A Super-fluid compound sun-screening agent and oil-in-water-in-oil triple sun-screening emulsion 广州嘉瑞亚微米生物技术有限公司 2023-12-05 CN disclosed
US-20040197361-A1 External preparation for the skin SHISEIDO COMPANY, LTD. (JP) 2004-10-07 US disclosed
EP-1430905-A1 EXTERNAL PREPARATION FOR THE SKIN SHISEIDO COMPANY LIMITED (JP) 2004-06-23 EP disclosed
US-6607736-B2 Endermic liniment comprising diethoxy ethyl succinate and humectant SHISEIDO COMPANY, LTD. (JP) 2003-08-19 US disclosed
US-20030091603-A1 Skin preparations for external use SHISEIDO COMPANY, LTD. (JP) 2003-05-15 US disclosed
EP-1230026-A1 ION EXCHANGE RESINS AND METHODS OF MAKING THE SAME BASF AKTIENGESELLSCHAFT (DE) 2002-08-14 EP disclosed
US-6417009-B1 COUPLING LIPID AUSTRALIAN MEMBRANE AND BIOTECHNOLOGY INSTITUTE (AU) 2002-07-09 US disclosed
EP-1153602-A1 SKIN PREPARATIONS FOR EXTERNAL USE SHISEIDO COMPANY LIMITED (JP) 2001-11-14 EP disclosed
WO-2001030495-A1 ION EXCHANGE RESINS AND METHODS OF MAKING THE SAME BASF AKTIENGESELLSCHAFT (DE) 2001-05-03 WO disclosed
US-4351738-A ETHYLENE OXIDE-PROPYLENE OXIDE COPOLYMER TEIJIN LIMITED (JP) 1982-09-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030091603-A1 Skin preparations for external use CUTA, POLR1C, ACMSD LMNA 524/4885L3MBTL1 490/4885TDP1 263/4885
US-11964043-B2 Method of emulsification using core-corona type microparticles LIPA, CORO1A, CLTA LMNA 360/4885L3MBTL1 4505/4885TDP1 2854/4885
US-20040197361-A1 External preparation for the skin CUTA, DDOST, DSG1 LMNA 2593/4885L3MBTL1 4235/4885TDP1 2076/4885
US-11931448-B2 Water-in-oil type emulsion composition FAM83A, LIPA, CUTA LMNA 154/4885L3MBTL1 1865/4885TDP1 1806/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.