Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | MGAM | O43451 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | SI | P14410 | 2/20 | 0.46 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.46 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.45 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.45 |
| ▸ | TUBB | P07437 | 1/20 | 0.45 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.45 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.45 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.45 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.45 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.45 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.45 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.45 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.45 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.45 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.45 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.45 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28035855 | 0.86 | RAB9A (0.50) | BCHEMGAMGAASIMGAM2 | |
| SCHEMBL17304630 | 0.84 | TNFRSF1A (0.50) | GAATUBB1TUBB4ATUBBTUBA3C | |
| SCHEMBL17304639 | 0.83 | PTPN11 (0.46) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL27908966 | 0.79 | RAB9A (0.50) | BCHEMGAMGAASIMGAM2 | |
| SCHEMBL17301353 | 0.78 | TUBB4A (0.62) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL17301352 | 0.76 | MAOB (0.46) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL17301356 | 0.75 | KRAS (0.47) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL27453865 | 0.75 | TNFRSF1A (0.54) | TNFRSF1AMEN1KMT2A | |
| SCHEMBL17304629 | 0.74 | APP (0.51) | GAATUBB1TUBB4ATUBBTUBA3C | |
| SCHEMBL712706 | 0.73 | CTSV (0.60) | MAOBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9573873-B2 | Catalytic method for dibenzocycloheptane synthesis and allocolchicinoid synthesis | UNIVERSITY OF WINDSOR (CA) | 2017-02-21 | — | — | US | disclosed |