SCHEMBL18533192

SCHEMBL18533192

Cc1ccc(-c2nc(-c3ccc(Br)c(C)c3)nc(-c3ccc(Br)c(C)c3)n2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.49
S1PR1 P21453 1/20 0.43
NPC1 O15118 7/20 0.41
RAB9A P51151 7/20 0.41
SMN1; SMN2 Q16637 4/20 0.41
NFKB1 P19838 2/20 0.41
NFKB2 Q00653 2/20 0.41
RELA Q04206 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
MAPK1 P28482 2/20 0.41
TP53 P04637 1/20 0.41
AHR P35869 1/20 0.39
NR1H4 Q96RI1 1/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
ADORA3 P0DMS8 2/20 0.38
TYMP P19971 1/20 0.37
ALDH1A1 P00352 3/20 0.37
NPSR1 Q6W5P4 2/20 0.37
CYP1A2 P05177 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10067982 0.92 S1PR1 (0.48) MAPTS1PR1NPC1RAB9ASMN1; SMN2
SCHEMBL18518742 0.87 L3MBTL1 (0.53) MAPTS1PR1NPC1RAB9ANFKB1
SCHEMBL19750260 0.82 NPC1 (0.46) MAPTS1PR1NPC1RAB9ASMN1; SMN2
SCHEMBL25404694 0.81 S1PR1 (0.42) MAPTS1PR1NPC1RAB9AMEN1
SCHEMBL31453990 0.81 L3MBTL1 (0.52) MAPTS1PR1NPC1RAB9ASMN1; SMN2
SCHEMBL12440897 0.81 ALDH1A1 (0.46) MAPTS1PR1NPC1RAB9ASMN1; SMN2
SCHEMBL15025812 0.78 NPC1 (0.41) NPC1RAB9ASMN1; SMN2NFKB1NFKB2
SCHEMBL11810896 0.78 L3MBTL1 (0.52) NPC1RAB9ANFKB1NFKB2RELA
SCHEMBL6111135 0.78 L3MBTL1 (0.52) NPC1RAB9ANFKB1NFKB2RELA
SCHEMBL15281176 0.78 ADORA3 (0.45) MAPTNPC1RAB9ANFKB1NFKB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3133660-B1 COMPOSITION AND LIGHT-EMITTING ELEMENT USING SAME SUMITOMO CHEMICAL CO (JP) 2020-01-29 EP disclosed
US-10347840-B2 Organic light-emitting polymer and device CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2019-07-09 US disclosed
US-9905767-B2 High-molecular compound and light-emitting element using same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-02-27 US disclosed
EP-3133660-A1 COMPOSITION AND LIGHT-EMITTING ELEMENT USING SAME Sumitomo Chemical Company Limited (JP) 2017-02-22 EP disclosed