SCHEMBL18533243

SCHEMBL18533243

C=C1COc2c1ccc1ccccc21

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 4/20 0.40
ALDH1A1 P00352 5/20 0.39
HSD17B10 Q99714 3/20 0.39
TSHR P16473 2/20 0.39
CYP2A6 P11509 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
HPRT1 P00492 1/20 0.37
KDM4E B2RXH2 2/20 0.36
MAPT P10636 2/20 0.36
MEN1 O00255 2/20 0.36
TP53 P04637 2/20 0.36
HPGD P15428 2/20 0.36
MAPK1 P28482 2/20 0.36
KMT2A Q03164 2/20 0.36
HTT P42858 1/20 0.36
HCRTR1 O43613 1/20 0.36
KIF11 P52732 1/20 0.35
HIF1A Q16665 2/20 0.35
USP2 O75604 1/20 0.35
LMNA P02545 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29817387 0.86 ALDH1A1 (0.44) CYP19A1ALDH1A1HSD17B10TSHRCYP2A6
SCHEMBL86747 0.78 CYP19A1 (0.54) CYP19A1ALDH1A1HSD17B10TSHRCYP2A6
SCHEMBL6453627 0.76 MAOA (0.46) CYP19A1ALDH1A1HSD17B10TSHRCYP2A6
SCHEMBL29951707 0.74 CYP19A1 (0.38) CYP19A1ALDH1A1HSD17B10TSHRCYP2A6
SCHEMBL24710437 0.71 ALDH1A1 (0.45) CYP19A1ALDH1A1HSD17B10TSHRCYP2A6
SCHEMBL4446478 0.70 CYP19A1 (0.43) CYP19A1ALDH1A1MAPTCYP1A2
SCHEMBL23259243 0.69 MAOA (0.41) ALDH1A1HSD17B10TSHRTDP1KDM4E
SCHEMBL14803714 0.69 ALDH1A1 (0.38) CYP19A1ALDH1A1HSD17B10TSHRCYP2A6
SCHEMBL86802 0.68 CYP19A1 (0.51) CYP19A1ALDH1A1HSD17B10TSHRKDM4E
SCHEMBL6437588 0.67 KDM4E (0.46) ALDH1A1CYP2A6TDP1KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2053095-B2 Ink composition and inkjet recording method using the same FUJIFILM CORP (JP) 2017-02-22 EP disclosed