Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL86747 | 0.74 | CYP19A1 (0.54) | CYP19A1ALDH1A1KDM4EMAPTHCRTR1 | |
| SCHEMBL18533243 | 0.74 | CYP19A1 (0.40) | CYP19A1ALDH1A1KDM4EMAPTHCRTR1 | |
| SCHEMBL29817387 | 0.72 | ALDH1A1 (0.44) | CYP19A1ALDH1A1KDM4EMAPTHCRTR1 | |
| SCHEMBL6453627 | 0.69 | MAOA (0.46) | CYP19A1ALDH1A1KDM4EMAPTHCRTR1 | |
| SCHEMBL30354655 | 0.68 | CA12 (0.39) | CYP19A1ALDH1A1KDM4EMAPTHCRTR1 | |
| SCHEMBL21591513 | 0.68 | CA12 (0.39) | CYP19A1ALDH1A1KDM4EMAPTHCRTR1 | |
| SCHEMBL30354656 | 0.68 | CA12 (0.39) | CYP19A1ALDH1A1KDM4EMAPTHCRTR1 | |
| SCHEMBL5657363 | 0.68 | KDM4E (0.41) | CYP19A1ALDH1A1KDM4EMAPTHCRTR1 | |
| SCHEMBL4446478 | 0.67 | CYP19A1 (0.43) | CYP19A1ALDH1A1MAPT | |
| SCHEMBL86802 | 0.65 | CYP19A1 (0.51) | CYP19A1ALDH1A1KDM4EMAPTHCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |