Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24197359 | 0.82 | THRA (0.35) | — | |
| SCHEMBL19922294 | 0.78 | PIK3CD (0.33) | PIK3CD | |
| SCHEMBL25936320 | 0.76 | THRA (0.47) | PIK3CD | |
| SCHEMBL18520076 | 0.75 | CES2 (0.50) | — | |
| SCHEMBL24790537 | 0.73 | THRA (0.35) | — | |
| SCHEMBL1370837 | 0.72 | — | — | |
| SCHEMBL16095403 | 0.71 | — | — | |
| SCHEMBL28822104 | 0.71 | MAPT (0.31) | — | |
| SCHEMBL18056354 | 0.71 | PIK3CD (0.30) | PIK3CD | |
| SCHEMBL28686853 | 0.71 | CHRNB2 (0.37) | PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9745305-B2 | Modulators of methyl modifying enzymes, compositions and uses thereof | CONSTELLATION PHARMACEUTICALS, INC. (US) | 2017-08-29 | — | — | US | disclosed |
| EP-2970305-B1 | MODULATORS OF METHYL MODIFYING ENZYMES, COMPOSITIONS AND USES THEREOF | CONSTELLATION PHARMACEUTICALS INC (US) | 2017-02-22 | — | — | EP | disclosed |