Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Levodopa. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 known ✓ | P35462 | 1/20 | 0.53 |
| ▸ | SLC7A5 | Q01650 | 6/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 1.00 |
| ▸ | ALOX15 | P16050 | 5/20 | 1.00 |
| ▸ | HIF1A | Q16665 | 5/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 1.00 |
| ▸ | USP2 | O75604 | 4/20 | 1.00 |
| ▸ | RECQL | P46063 | 4/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 1.00 |
| ▸ | PTGS1 | P23219 | 2/20 | 1.00 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 1.00 |
| ▸ | HTR2A | P28223 | 2/20 | 1.00 |
| ▸ | PTGS2 | P35354 | 2/20 | 1.00 |
| ▸ | EGFR | P00533 | 1/20 | 1.00 |
| ▸ | LCK | P06239 | 1/20 | 1.00 |
| ▸ | FYN | P06241 | 1/20 | 1.00 |
| ▸ | KDM6B | O15054 | 1/20 | 0.66 |
| ▸ | PKM | P14618 | 3/20 | 0.58 |
| ▸ | ALPI | P09923 | 1/20 | 0.58 |
| ▸ | XIAP | P98170 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Levodopa SCHEMBL24360 | 1.00 | SLC7A5 (1.00) | SLC7A5KDM4EALOX15HIF1AHSD17B10 | |
| Levodopa SCHEMBL704089 | 1.00 | SLC7A5 (1.00) | SLC7A5KDM4EALOX15HIF1AHSD17B10 | |
| Levodopa SCHEMBL29373537 | 1.00 | SLC7A5 (1.00) | SLC7A5KDM4EALOX15HIF1AHSD17B10 | |
| Levodopa SCHEMBL29974762 | 1.00 | SLC7A5 (1.00) | SLC7A5KDM4EALOX15HIF1AHSD17B10 | |
| Levodopa SCHEMBL11000382 | 1.00 | SLC7A5 (1.00) | SLC7A5KDM4EALOX15HIF1AHSD17B10 | |
| Levodopa SCHEMBL116907 | 1.00 | SLC7A5 (1.00) | SLC7A5KDM4EALOX15HIF1AHSD17B10 | |
| Levodopa SCHEMBL30678311 | 1.00 | SLC7A5 (1.00) | SLC7A5KDM4EALOX15HIF1AHSD17B10 | |
| Levodopa SCHEMBL22655 | 1.00 | SLC7A5 (1.00) | SLC7A5KDM4EALOX15HIF1AHSD17B10 | |
| Levodopa SCHEMBL29975814 | 1.00 | SLC7A5 (1.00) | SLC7A5KDM4EALOX15HIF1AHSD17B10 | |
| Levodopa SCHEMBL20582239 | 1.00 | SLC7A5 (1.00) | SLC7A5KDM4EALOX15HIF1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 157 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117944274-A | Auxiliary welding process for flow battery | 中海储能科技(北京)有限公司 | 2024-04-30 | — | — | CN | claimed |
| CN-113354786-B | Method for preparing difunctional polyether-ether-ketone by using mussel derived peptide and biological orthogonal reaction and application thereof | 苏州大学附属第一医院 | 2023-07-04 | — | — | CN | claimed |
| CN-115428807-A | Ti-SSC-Ag sterilization material and preparation method and application thereof | 西南大学 | 2022-12-06 | — | — | CN | claimed |
| CN-113144290-B | Orthopedic material surface coating for promoting bone and immune regulation and preparation method thereof | 苏州大学附属第一医院 | 2022-08-23 | — | — | CN | claimed |
| CN-114124622-B | Data identification processing system for silent communication | 天津大学 | 2022-05-17 | — | — | CN | claimed |
| CN-114124622-A | Data identification processing system for silent communication | 天津大学 | 2022-03-01 | — | — | CN | claimed |
| CN-113354786-A | Method for preparing difunctional polyether-ether-ketone by using mussel-derived peptide in combination with bioorthogonal reaction and application thereof | 苏州大学附属第一医院 | 2021-09-07 | — | — | CN | claimed |
| CN-113144290-A | Orthopedic material surface coating for promoting bone and immune regulation and preparation method thereof | 苏州大学附属第一医院 | 2021-07-23 | — | — | CN | claimed |
| CN-105143245-B | Anti-scaling material | 耶路撒冷希伯来大学伊森姆研究发展有限公司 | 2021-02-05 | — | — | CN | claimed |
| CN-110106708-A | A kind of non-iris structure yarn dyed fabric and preparation method thereof | 苏州大学 | 2019-08-09 | — | — | CN | claimed |
| CN-107858217-A | STABILIZED SUBTILISIN COMPOSITION | 诺维信公司 | 2018-03-30 | — | — | CN | claimed |
| CN-107522827-A | A kind of photocuring 3D printing photosensitive resin and its preparation method and application | 杨军 | 2017-12-29 | — | — | CN | claimed |
| CN-103649292-B | Stabilized subtilisin compositions | 诺维信公司 | 2017-11-28 | — | — | CN | claimed |
| CN-106456665-A | Methods of promoting bone growth and healing | 宾夕法尼亚州研究基金会 | 2017-02-22 | — | — | CN | claimed |
| CN-103159944-A | Aromatic amino acid polymer | UNIV JIANGNAN | 2013-06-19 | — | — | CN | claimed |
| EP-0540676-B1 | PEPTIDE COMPOUNDS HAVING GROWTH HORMONE RELEASING ACTIVITY | POLYGEN HOLDING CORP (US) | 1994-11-17 | — | — | EP | claimed |
| EP-0417165-A1 | POLYPEPTIDE COMPOUNDS HAVING GROWTH HORMONE RELEASING ACTIVITY. | EASTMAN KODAK CO (US) | 1991-03-20 | — | — | EP | claimed |
| EP-0400051-A1 | POLYPEPTIDE COMPOUNDS HAVING GROWTH HORMONE RELEASING ACTIVITY. | EASTMAN KODAK CO (US) | 1990-12-05 | — | — | EP | claimed |
| WO-1989010933-A1 | POLYPEPTIDE COMPOUNDS HAVING GROWTH HORMONE RELEASING ACTIVITY | EASTMAN KODAK COMPANY (US) | 1989-11-16 | — | — | WO | claimed |
| WO-1989007110-A1 | POLYPEPTIDE COMPOUNDS HAVING GROWTH HORMONE RELEASING ACTIVITY | EASTMAN KODAK COMPANY (US) | 1989-08-10 | — | — | WO | claimed |