Levodopa

Levodopa

SCHEMBL24360

NC(Cc1ccc(O)c(O)c1)C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

DRD3

The experimentally established mechanism targets of Levodopa. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD3 known ✓ P35462 1/20 0.53
SLC7A5 Q01650 6/20 1.00
KDM4E B2RXH2 5/20 1.00
ALOX15 P16050 5/20 1.00
HIF1A Q16665 5/20 1.00
HSD17B10 Q99714 5/20 1.00
USP2 O75604 4/20 1.00
RECQL P46063 4/20 1.00
TDP1 Q9NUW8 4/20 1.00
PTGS1 P23219 2/20 1.00
ADORA3 P0DMS8 2/20 1.00
HTR2A P28223 2/20 1.00
PTGS2 P35354 2/20 1.00
EGFR P00533 1/20 1.00
LCK P06239 1/20 1.00
FYN P06241 1/20 1.00
KDM6B O15054 1/20 0.66
PKM P14618 3/20 0.58
ALPI P09923 1/20 0.58
XIAP P98170 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Levodopa SCHEMBL704089 1.00 SLC7A5 (1.00) SLC7A5KDM4EALOX15HIF1AHSD17B10
Levodopa SCHEMBL29373537 1.00 SLC7A5 (1.00) SLC7A5KDM4EALOX15HIF1AHSD17B10
Levodopa SCHEMBL29974762 1.00 SLC7A5 (1.00) SLC7A5KDM4EALOX15HIF1AHSD17B10
Levodopa SCHEMBL11000382 1.00 SLC7A5 (1.00) SLC7A5KDM4EALOX15HIF1AHSD17B10
Levodopa SCHEMBL116907 1.00 SLC7A5 (1.00) SLC7A5KDM4EALOX15HIF1AHSD17B10
Levodopa SCHEMBL30678311 1.00 SLC7A5 (1.00) SLC7A5KDM4EALOX15HIF1AHSD17B10
Levodopa SCHEMBL22655 1.00 SLC7A5 (1.00) SLC7A5KDM4EALOX15HIF1AHSD17B10
Levodopa SCHEMBL29975814 1.00 SLC7A5 (1.00) SLC7A5KDM4EALOX15HIF1AHSD17B10
Levodopa SCHEMBL20582239 1.00 SLC7A5 (1.00) SLC7A5KDM4EALOX15HIF1AHSD17B10
Levodopa SCHEMBL1853441 1.00 SLC7A5 (1.00) SLC7A5KDM4EALOX15HIF1AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 42741 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4746858-A2 COATED NANOPARTICLES AND THEIR USE FOR DELIVERY OF THERAPEUTIC AND DIAGNOSTIC AGENTS Politecnico Di Torino (IT) 2026-05-27 EP claimed
EP-4746852-A1 LIPID AGGREGATES FOR INTRAARTICULAR ADMINISTRATION Universität Bern (CH) 2026-05-27 EP claimed
CN-122081191-A Engineering bacterium for producing high-modified mussel protein by in-vivo fermentation and application thereof 2026-05-26 CN claimed
CN-122094701-A TLR3 binding bicyclic peptide ligands 2026-05-26 CN claimed
CN-122068341-A Dopa series assembly and pumped solid state laser 西安炬光科技股份有限公司 2026-05-19 CN claimed
WO-2026100654-A1 NUCLEIC ACID INTRODUCTION AID, NUCLEIC ACID INTRODUCTION AGENT, AND NUCLEIC ACID INTRODUCTION METHOD 株式会社インファーマシア 2026-05-15 WO claimed
CN-122037641-A Corrosion-resistant protective varnish for automobile air inlet grille and preparation method thereof 长春富维高新汽车饰件有限公司 2026-05-15 CN claimed
WO-2026099867-A1 SUSTAINABLE ANTIFREEZE COATINGS BY PEPTIDE SELF-ASSEMBLY YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) 2026-05-15 WO claimed
CN-122032319-A Super-hydrophilic polymer separation membrane and preparation method and application thereof 中国石油化工股份有限公司 2026-05-15 CN claimed
EP-3869192-B1 METHOD FOR QUANTITATIVE DETECTION OF VARIOUS METABOLITES IN BIOLOGICAL SAMPLE HUMAN METABOLOMICS INST INC (CN) 2026-05-13 EP claimed
US-4144133-A OXGALL, SAPONIN, SUBSTRATE FOR PHENOL OXIDASE J. K. AND SUSIE L. WADLEY RESEARCH INSTITUTE AND BLOOD BANK (US) 1979-03-13 US claimed
US-4122078-A Antigens and antibodies of catecholamines DAIICHI SEIYAKU CO., LTD. (JP) 1978-10-24 US claimed
US-4116949-A WATER-SOLUBLE, PHYSIOLOGICALLY ACTIVE, SYNTHETIC COPOLYPEPTIDES THE REAGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1978-09-26 US claimed
US-4111863-A NON-SWELLABLE, THREE DIMENSIONAL DYNAMIT NOBEL AKTIENGESELLSCHAFT (DE) 1978-09-05 US claimed
US-4042329-A Method and device for detecting cholesterol BECTON, DICKINSON AND COMPANY (US) 1977-08-16 US claimed
US-3991207-A TETRAHYDRONAPHTHYLAMINES AND L-3,4-DIHYDROXYPHENYL-ALANINE PFIZER INC. (US) 1976-11-09 US claimed
US-3983234-A CLOZAPINE SANDOZ LTD. (CH) 1976-09-28 US claimed
US-3972918-A Process for separating DOPA from tyrosine THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 1976-08-03 US claimed
US-3964871-A GLUCOSE OXIDASE, HORSERADISH PEROXIDASE BECTON, DICKINSON AND COMPANY (US) 1976-06-22 US claimed
US-3961060-A DOPA, M-TYROSINE, APOMORPHINE, PIPERAZINE DERIVATIVE ASTRA LAKEMEDAL AKTIEBOLAG (SW) 1976-06-01 US claimed