Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5226719 | 0.80 | CA2 (0.44) | ALOX12PGRCA2 | |
| SCHEMBL14751280 | 0.79 | ALOX12 (0.40) | ALOX12PGRCA2 | |
| SCHEMBL3072904 | 0.72 | CD44 (0.48) | PGRCA2 | |
| SCHEMBL23162712 | 0.71 | PGR (0.45) | PGRCA2 | |
| SCHEMBL29636630 | 0.71 | PGR (0.45) | PGRCA2 | |
| SCHEMBL25510426 | 0.71 | PGR (0.38) | PGRCA2 | |
| SCHEMBL18534926 | 0.70 | PGR (0.35) | PGRCA2 | |
| SCHEMBL20430118 | 0.70 | CD44 (0.50) | CA2 | |
| SCHEMBL14985755 | 0.69 | ALOX12 (0.62) | ALOX12CA2 | |
| SCHEMBL14221243 | 0.69 | CD44 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2763990-B1 | PYRROLOPYRAZINE KINASE INHIBITORS | HOFFMANN LA ROCHE (CH) | 2017-02-22 | — | — | EP | disclosed |