Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.40 |
| ▸ | ILK | Q13418 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL438207 | 0.88 | MAPT (0.53) | MAPTNR4A2HSP90AA1NPC1HSP90AB1 | |
| SCHEMBL439448 | 0.83 | NR4A2 (0.59) | MAPTNR4A2HSP90AA1HSP90AB1CRHR1 | |
| SCHEMBL437233 | 0.80 | NR4A2 (0.51) | MAPTNR4A2HSP90AA1HSP90AB1RAB9A | |
| SCHEMBL6087451 | 0.78 | MAPT (0.44) | MAPTNR4A2HSP90AA1NPC1HSP90AB1 | |
| SCHEMBL2871982 | 0.75 | MAPT (0.57) | MAPTNR4A2HSP90AA1NPC1HSP90AB1 | |
| SCHEMBL18535210 | 0.71 | MAPT (0.83) | MAPTNPC1RAB9AALDH1A1NQO2 | |
| SCHEMBL437287 | 0.71 | NR4A2 (0.61) | MAPTNR4A2HSP90AA1NPC1RAB9A | |
| SCHEMBL17502192 | 0.71 | MAPT (0.60) | MAPTNR4A2HSP90AA1NPC1RAB9A | |
| SCHEMBL11637772 | 0.70 | KDM4E (0.50) | MAPTNR4A2RAB9ACRHR1ALDH1A1 | |
| SCHEMBL29091655 | 0.70 | ALDH1A1 (0.43) | MAPTNPC1RAB9AILKALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |