Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 7/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALB | P02768 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10160802 | 1.00 | ADK (0.64) | ADKALDH1A1LMNAALBMAPK1 | |
| SCHEMBL10160860 | 0.81 | ADK (0.65) | ADKALDH1A1LMNAALBMAPK1 | |
| SCHEMBL23584606 | 0.79 | ADK (0.42) | ADKALDH1A1LMNAALBMAPK1 | |
| SCHEMBL10161661 | 0.78 | ADK (1.00) | ADK | |
| SCHEMBL314676 | 0.78 | ADK (1.00) | ADK | |
| SCHEMBL21370966 | 0.77 | ADK (0.65) | ADKALDH1A1LMNAALBMAPK1 | |
| SCHEMBL25948511 | 0.77 | ALDH1A1 (0.39) | ADKALDH1A1LMNAALBMAPK1 | |
| SCHEMBL25076431 | 0.77 | ALDH1A1 (0.39) | ADKALDH1A1LMNAALBMAPK1 | |
| SCHEMBL23809695 | 0.75 | ADK (0.46) | ADK | |
| SCHEMBL21371090 | 0.74 | ADK (0.67) | ADK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3133080-B1 | NOVEL CYTOSTATIC 7-DEAZAPURINE NUCLEOSIDES | INST OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) | 2018-08-01 | — | — | EP | disclosed |
| EP-3133080-A1 | NOVEL CYTOSTATIC 7-DEAZAPURINE NUCLEOSIDES | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) | 2017-02-22 | — | — | EP | disclosed |