Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALB | P02768 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ADK | P55263 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25076431 | 1.00 | ALDH1A1 (0.39) | ALDH1A1LMNAALBMAPK1ADK | |
| SCHEMBL23584606 | 0.84 | ADK (0.42) | ALDH1A1LMNAALBMAPK1ADK | |
| SCHEMBL18535222 | 0.77 | ADK (0.64) | ALDH1A1LMNAALBMAPK1ADK | |
| SCHEMBL10160802 | 0.77 | ADK (0.64) | ALDH1A1LMNAALBMAPK1ADK | |
| SCHEMBL10160860 | 0.76 | ADK (0.65) | ALDH1A1LMNAALBMAPK1ADK | |
| SCHEMBL25048783 | 0.76 | ADK (0.44) | ALDH1A1LMNAALBMAPK1ADK | |
| SCHEMBL23641741 | 0.75 | ADK (0.43) | ALDH1A1LMNAALBMAPK1ADK | |
| SCHEMBL10266132 | 0.75 | ADK (0.54) | ALDH1A1LMNAALBMAPK1ADK | |
| SCHEMBL19120374 | 0.75 | ADK (0.54) | ALDH1A1LMNAALBMAPK1ADK | |
| SCHEMBL23584555 | 0.75 | ADK (0.54) | ALDH1A1LMNAALBMAPK1ADK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219496-A1 | NOVEL 6-6 BICYCLIC AROMATIC RING SUBSTITUTED NUCLEOSIDE ANALOGUES FOR USE AS PRMT5 INHIBITORS | JANSSEN Pharmaceutica NV (BE) | 2023-08-02 | — | — | EP | disclosed |