Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 13/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.51 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | APAF1 | O14727 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | STAT6 | P42226 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22625522 | 0.89 | MIF (0.67) | MIFNPC1ESR2PTGS1MEN1 | |
| SCHEMBL27844746 | 0.83 | GAA (0.58) | MIFNPC1ESR2PTGS1AKR1B10 | |
| SCHEMBL18535548 | 0.80 | ESR2 (0.49) | MIFNPC1ESR2PTGS1AKR1B10 | |
| SCHEMBL4527127 | 0.79 | HSD17B3 (0.55) | MIFESR2PTGS1AKR1B10AKR1B1 | |
| SCHEMBL4251337 | 0.78 | HSD17B3 (0.54) | MIFNPC1ESR2MEN1KMT2A | |
| SCHEMBL24595591 | 0.78 | ESR2 (0.49) | MIFNPC1ESR2PTGS1AKR1B10 | |
| SCHEMBL1706856 | 0.77 | MIF (0.74) | MIFNPC1ESR2PTGS1MEN1 | |
| SCHEMBL30108452 | 0.77 | MIF (0.74) | MIFNPC1ESR2PTGS1MEN1 | |
| SCHEMBL17128796 | 0.77 | ALDH1A1 (0.46) | AKR1B10AKR1B1MEN1KMT2ALMNA | |
| Water SCHEMBL27385678 | 0.77 | HSD17B3 (0.52) | MIFNPC1ESR2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3502147-A1 | COMPOSITION FOR OPHTHALMOLOGICAL PRODUCTS | Merck Patent GmbH (DE) | 2019-06-26 | — | — | EP | disclosed |
| EP-3133065-A1 | COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | Merck Patent GmbH (DE) | 2017-02-22 | — | — | EP | disclosed |