Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.40 |
| ▸ | NPC1 | O15118 | 8/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.40 |
| ▸ | HPGD | P15428 | 6/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | GLA | P06280 | 5/20 | 0.40 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | SLC16A3 | O15427 | 3/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27105690 | 0.85 | KLK7 (0.41) | RAB9ANPC1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL18535566 | 0.81 | RAB9A (0.45) | RAB9ANPC1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL26854645 | 0.78 | KLK7 (0.42) | RAB9ANPC1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL18535609 | 0.78 | KLK7 (0.40) | RAB9ANPC1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL27106451 | 0.78 | HIF1A (0.35) | RAB9ANPC1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL21116161 | 0.78 | NPC1 (0.39) | RAB9ANPC1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL23713541 | 0.77 | RAB9A (0.44) | RAB9ANPC1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL18535495 | 0.76 | GLA (0.65) | RAB9ANPC1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL21524260 | 0.75 | NPC1 (0.47) | RAB9ANPC1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL18583701 | 0.75 | NPC1 (0.62) | RAB9ANPC1KDM4EHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3133065-A1 | COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | Merck Patent GmbH (DE) | 2017-02-22 | — | — | EP | disclosed |