Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.44 |
| ▸ | NPC1 | O15118 | 9/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.41 |
| ▸ | GLA | P06280 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 8/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | GAA | P10253 | 6/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MIF | P14174 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KLK7 | P49862 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18583701 | 0.86 | NPC1 (0.62) | RAB9ANPC1KDM4EGLAMAOB | |
| SCHEMBL21524260 | 0.84 | NPC1 (0.47) | RAB9ANPC1KDM4EGLAKMT2A | |
| SCHEMBL23713542 | 0.83 | RAB9A (0.51) | RAB9ANPC1KDM4EGLAKMT2A | |
| SCHEMBL23713534 | 0.83 | MIF (0.46) | RAB9ANPC1KDM4EGLAKMT2A | |
| SCHEMBL18535566 | 0.83 | RAB9A (0.45) | RAB9ANPC1KDM4EGLAKMT2A | |
| SCHEMBL18535495 | 0.82 | GLA (0.65) | RAB9ANPC1KDM4EGLAKMT2A | |
| SCHEMBL18535716 | 0.80 | MIF (0.62) | RAB9ANPC1KDM4EGLAKMT2A | |
| SCHEMBL18535609 | 0.79 | KLK7 (0.40) | RAB9ANPC1KDM4EGLAKMT2A | |
| SCHEMBL27105690 | 0.77 | KLK7 (0.41) | RAB9ANPC1KDM4EGLAKMT2A | |
| SCHEMBL18535568 | 0.77 | RAB9A (0.40) | RAB9ANPC1KDM4EGLAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11078177-B2 | Compounds for optically active devices | MERCK PATENT GMBH (DE) | 2021-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11078177-B2 | Compounds for optically active devices | PDE6C, ALDH1A2, PDE6A | RAB9A 930/4885NPC1 2482/4885KDM4E 4039/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.