Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 13/20 | 0.60 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | GLA | P06280 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18535686 | 0.81 | NPC1 (0.46) | MIFRAB9AKDM4EALDH1A1MEN1 | |
| SCHEMBL2167401 | 0.78 | MIF (0.71) | MIFRAB9AKDM4EALDH1A1MEN1 | |
| SCHEMBL23713470 | 0.76 | MIF (0.68) | MIFRAB9AKDM4EALDH1A1MEN1 | |
| SCHEMBL18535688 | 0.76 | RAB9A (0.40) | MIFRAB9AKDM4EALDH1A1MEN1 | |
| SCHEMBL18535409 | 0.76 | MIF (0.60) | MIFRAB9AKDM4EALDH1A1MEN1 | |
| SCHEMBL2552347 | 0.75 | MIF (1.00) | MIFRAB9AKDM4EALDH1A1MEN1 | |
| SCHEMBL24046291 | 0.75 | RAB9A (0.39) | MIFRAB9AKDM4EALDH1A1MEN1 | |
| SCHEMBL22625522 | 0.74 | MIF (0.67) | MIFRAB9AKDM4EALDH1A1MEN1 | |
| SCHEMBL18583707 | 0.72 | MIF (0.71) | MIFRAB9AKDM4EALDH1A1MEN1 | |
| SCHEMBL21761551 | 0.71 | MIF (0.61) | MIFRAB9AKDM4EALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3133065-A1 | COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | Merck Patent GmbH (DE) | 2017-02-22 | — | — | EP | disclosed |