Sugi Predict

Sugi Predict / Compounds / E122

E122

E122

SCHEMBL185359

O=S(=O)(O)c1ccc(/N=N/c2cc(S(=O)(=O)O)c3ccccc3c2O)c2ccccc12.[NaH].[NaH]

nearest known ligand 0.76

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP1A2 P05177 2/20 0.76
▸ THRB P10828 3/20 0.70
▸ CTRB1 P17538 1/20 0.70
▸ MEN1 O00255 3/20 0.57
▸ KMT2A Q03164 3/20 0.57
▸ TDP1 Q9NUW8 2/20 0.57
▸ MPL P40238 3/20 0.55
▸ CTRC Q99895 1/20 0.55
▸ HPGD P15428 2/20 0.52
▸ BLM P54132 2/20 0.52
▸ ALDH1A1 P00352 1/20 0.52
▸ APP P05067 1/20 0.52
▸ MAPT P10636 1/20 0.52
▸ ALOX12 P18054 1/20 0.52
▸ SNCA P37840 1/20 0.52
▸ RECQL P46063 1/20 0.52
▸ HIF1A Q16665 1/20 0.52
▸ SUMO2 P61956 4/20 0.51
▸ SUMO1 P63165 4/20 0.51
▸ SENP7 Q9BQF6 4/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
E122 SCHEMBL4806652 1.00 CYP1A2 (0.76) CYP1A2THRBCTRB1MEN1KMT2A
E122 SCHEMBL345295 0.98 CYP1A2 (0.78) CYP1A2THRBCTRB1MEN1KMT2A
E122 SCHEMBL110093 0.98 CYP1A2 (0.78) CYP1A2THRBCTRB1MEN1KMT2A
E122 SCHEMBL185360 0.97 CYP1A2 (0.76) CYP1A2THRBCTRB1MEN1KMT2A
E122 SCHEMBL4806638 0.89 THRB (0.90) CYP1A2THRBCTRB1MEN1KMT2A
E122 SCHEMBL3208444 0.89 THRB (0.90) CYP1A2THRBCTRB1MEN1KMT2A
SCHEMBL8947091 0.87 CYP1A2 (0.71) CYP1A2THRBCTRB1MEN1KMT2A
SCHEMBL6580682 0.87 CYP1A2 (0.71) CYP1A2THRBCTRB1MEN1KMT2A
SCHEMBL15424213 0.84 CYP1A2 (0.71) CYP1A2THRBCTRB1MEN1KMT2A
SCHEMBL626036 0.84 CYP1A2 (0.66) CYP1A2THRBCTRB1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2930126-B1 Fashionable aerosol dye HENKEL AG & CO KGAA (DE) 2019-10-09 — — EP claimed
US-7294370-B2 Polarizing and optical compensating films for visible, ultraviolet and infrared parts of the electromagnetic spectrum KENT STATE UNIVERSITY (US) 2007-11-13 — — US claimed
US-9173829-B2 Compositions for dyeing keratin fibers HENKEL AG & CO. KGAA (DE) 2015-11-03 — — US disclosed
US-9161898-B2 Compositions for colouring keratin fibres HENKEL AG & CO. KGAA (DE) 2015-10-20 — — US disclosed
US-9150788-B2 Non-amphiphile-based water-in-water emulsion and uses thereof SYRACUSE UNIVERSITY (US) 2015-10-06 — — US disclosed
US-20140298592-A1 COMPOSITIONS FOR DYEING KERATIN FIBERS HENKEL AG & CO. KGAA (DE) 2014-10-09 — — US disclosed
US-20140290690-A1 COMPOSITIONS FOR COLOURING KERATIN FIBRES HENKEL AG & CO. KGAA (DE) 2014-10-02 — — US disclosed
EP-1455740-B1 PROCESS FOR PREPARATION OF HAIR TREATMENT COMPOSITION COMPRISING COMPOSITE PARTICLES OF CLAY AND CHARGED ORGANIC MOLECULE UNILEVER PLC (GB) 2012-01-04 — — EP disclosed
EP-1844109-B1 USE OF CATIONIC AZACYANINE DYES FOR COLORING KERATIN FIBERS PROCTER & GAMBLE (US) 2011-03-30 — — EP disclosed
US-7749283-B2 Colorant with nacreous luster for keratin fibers WELLA AG (DE) 2010-07-06 — — US disclosed
US-7691398-B2 Hair treatment composition comprising composite particles of clay and charged organic molecule UNILEVER HOME & PERSONAL CARE USA DIVISION OF CONOPCO, INC. (US) 2010-04-06 — — US disclosed
US-6485529-B1 Agent and method for coloring fibers WELLA AKTIENGESELLSCHAFT (DE) 2002-11-26 — — US disclosed
US-6361571-B1 USING TAUTOMERIC NONOXIDATIVE DYES AND POLYMETHINE DYES WELLA AKTIENGESELLSCHAFT (DE) 2002-03-26 — — US disclosed
US-6171347-B1 REMOVAL OF HAIR COLOR TO BE WORN FOR ONLY A SHORT PERIOD OF TIME UNDER MILD, GENTLE CONDITIONS BY USING A COMBINATION OF A SUITABLE REDUCTONE, SUCH AS ASCORBIC ACID, AND/OR A THIOL AND/OR A SULFITE WELLA AKTIENGESELLSCHAFT (DE) 2001-01-09 — — US disclosed
US-5865855-A COUPLING TWO PYRAZOLE COMPOUNDS WELLA AKTIENGESELLSCHAFT (DE) 1999-02-02 — — US disclosed
US-4784959-A Method of detecting hydrocarbon fuel leaks LOCKHEED CORPORATION (US) 1988-11-15 — — US disclosed
US-4756854-A Method and apparatus for detecting hydrocarbon fuel leaks LOCKHEED CORPORATION (US) 1988-07-12 — — US disclosed
US-4745797-A Method and apparatus for detecting hydrocarbon fuel leaks LOCKHEED CORPORATION (US) 1988-05-24 — — US disclosed
US-4615828-A Method and apparatus for detecting hydrocarbon fuel leaks LOCKHEED CORPORATION (US) 1986-10-07 — — US disclosed
US-4323554-A MICA FLAKES AND A COLORED ALUMINUM LAKE FOR COSMETICS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1982-04-06 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140290690-A1 COMPOSITIONS FOR COLOURING KERATIN FIBRES KRT18, DSG1, PKN1 CYP1A2 1749/4885THRB 4544/4885CTRB1 2054/4885
US-20140298592-A1 COMPOSITIONS FOR DYEING KERATIN FIBERS KRT18, PKN3, IK CYP1A2 3680/4885THRB 3252/4885CTRB1 1577/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.