Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 4/20 | 0.35 |
| ▸ | CES2 | O00748 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29194858 | 0.86 | GAA (0.36) | SMN1; SMN2ALDH1A1MAPTTDP1LMNA | |
| SCHEMBL13982035 | 0.83 | CES2 (0.50) | SMN1; SMN2ALDH1A1MAPTCES1CES2 | |
| SCHEMBL665971 | 0.83 | CES2 (0.50) | SMN1; SMN2ALDH1A1MAPTCES1CES2 | |
| SCHEMBL30478610 | 0.83 | CES2 (0.50) | SMN1; SMN2ALDH1A1MAPTCES1CES2 | |
| SCHEMBL3312136 | 0.83 | CES2 (0.50) | SMN1; SMN2ALDH1A1MAPTCES1CES2 | |
| SCHEMBL23457203 | 0.82 | SMN1; SMN2 (0.37) | SMN1; SMN2ALDH1A1MAPTCES1CES2 | |
| SCHEMBL4738627 | 0.78 | CES2 (0.56) | SMN1; SMN2ALDH1A1MAPTCES1CES2 | |
| SCHEMBL29026524 | 0.77 | LMNA (0.37) | SMN1; SMN2ALDH1A1MAPTCES1CES2 | |
| SCHEMBL194429 | 0.77 | SMN1; SMN2 (0.45) | SMN1; SMN2ALDH1A1MAPTCES1CES2 | |
| SCHEMBL13875404 | 0.77 | SMN1; SMN2 (0.45) | SMN1; SMN2ALDH1A1MAPTCES1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1910425-B1 | PHOTOPOLYMERISABLE SYSTEMS CONTAINING LOW-EXTRACTABLE AND LOW-VOLATILE COINITIATORS | LAMBERTI SPA (IT) | 2011-05-25 | — | — | EP | claimed |